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phospho-CDK1 [cytosol]
Stable Identifier
R-CFA-157415
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
p-T161-CDK1, A0A8I3N3V4
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Nuclear Envelope (NE) Reassembly (Canis familiaris)
Initiation of Nuclear Envelope (NE) Reformation (Canis familiaris)
CDK1 phosphorylates LBR (Canis familiaris)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Mitotic Prometaphase (Canis familiaris)
Resolution of Sister Chromatid Cohesion (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Canis familiaris)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Mitotic Prophase (Canis familiaris)
Nuclear Envelope Breakdown (Canis familiaris)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Canis familiaris)
CDK1:CCNB phosphorylates NEK9 (Canis familiaris)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Nuclear Pore Complex (NPC) Disassembly (Canis familiaris)
CDK1 phosphorylates NUP98 (Canis familiaris)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Mitotic G2-G2/M phases (Canis familiaris)
G2/M Transition (Canis familiaris)
Cyclin A/B1/B2 associated events during G2/M transition (Canis familiaris)
Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B (Canis familiaris)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Phosphorylation of Cyclin B1 in the CRS domain (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CRS kinase [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
phospho-cyclin B1(CRS):phosph-Cdc2(Thr 161) [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Translocation of CRS phosphorylated Cyclin B1:Cdc2 complexes (Canis familiaris)
phospho-cyclin B1(CRS):phosph-Cdc2(Thr 161) [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Translocation of Cyclin B1:phospho-Cdc2 complexes to the nucleus (Canis familiaris)
cytoplasmic Cyclin B1:Cdc2 complexes [cytosol] (Canis familiaris)
phospho-cyclin B1(CRS):phosph-Cdc2(Thr 161) [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Regulation of PLK1 Activity at G2/M Transition (Canis familiaris)
CDK1 phosphorylates BORA (Canis familiaris)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
The role of GTSE1 in G2/M progression after G2 checkpoint (Canis familiaris)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Canis familiaris)
Mitotic kinase [cytosol] (Canis familiaris)
CCNB1,CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Regulation of mitotic cell cycle (Canis familiaris)
APC/C-mediated degradation of cell cycle proteins (Canis familiaris)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Canis familiaris)
APC/C:Cdc20 mediated degradation of mitotic proteins (Canis familiaris)
APC/C:Cdc20 mediated degradation of Cyclin B (Canis familiaris)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Degradation of multiubiquitinated Cyclin B (Canis familiaris)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Canis familiaris)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Canis familiaris)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Canis familiaris)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Canis familiaris)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Canis familiaris)
Association of Cyclin A with the APC/C (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Degradation multiubiquitinated Cyclin A (Canis familiaris)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Canis familiaris)
phospho-CDK1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3N3V4
Gene Names
CDK1
Reference Genes
BioGPS Gene:100856079 CDK1
ENSEMBL:ENSCAFG00845002973.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845002973.1 CDK1
KEGG Gene (Canis lupus familiaris):100856079 CDK1
Monarch:100856079 CDK1
NCBI Gene:100856079 CDK1
Reference Transcript
RefSeq:XM_005618901.2 CDK1
RefSeq:XM_014112825.1 CDK1
RefSeq:XM_005618900.1 CDK1
RefSeq:XM_014112824.1 CDK1
RefSeq:XM_003639013.3 CDK1
Other Identifiers
100856079
Cfa.20663.1.A1_at
Cfa.20663.1.A1_s_at
CfaAffx.20006.1.S1_at
GO:0000166
GO:0000278
GO:0000307
GO:0003682
GO:0003824
GO:0004672
GO:0004674
GO:0004693
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005759
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005876
GO:0006091
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0006357
GO:0006468
GO:0007010
GO:0007059
GO:0007095
GO:0008353
GO:0010971
GO:0012501
GO:0016301
GO:0016740
GO:0023052
GO:0030154
GO:0030332
GO:0030496
GO:0030544
GO:0030855
GO:0034501
GO:0035173
GO:0036211
GO:0042752
GO:0043066
GO:0043226
GO:0044772
GO:0048144
GO:0048856
GO:0062033
GO:0072686
GO:0097122
GO:0097125
GO:0097472
GO:0140014
GO:0140096
GO:1900182
GO:1902850
GO:1905448
Participates
as an output of
Degradation of multiubiquitinated Cyclin B (Canis familiaris)
Degradation multiubiquitinated Cyclin A (Canis familiaris)
as a component of
Cyclin A:phospho-Cdc2(Thr 161) complex [cytosol] (Canis familiaris)
CCNB2:p-T161-CDK1 [cytosol] (Canis familiaris)
CCNB1:p-T161-CDK1 [cytosol] (Canis familiaris)
phospho-cyclin B1(CRS):phosph-Cdc2(Thr 161) [cytosol] (Canis familiaris)
Other forms of this molecule
CDK1 [endoplasmic reticulum membrane]
phospho-CDK1 [cytosol]
phospho-CDK1 [nucleoplasm]
phospho-CDK1 [nucleoplasm]
phospho-CDK1 [cytosol]
CDK1 [nucleoplasm]
CDK1 [cytosol]
phospho-CDK1 [cytosol]
phospho-CDK1 [nucleoplasm]
phospho-CDK1 [nucleoplasm]
Inferred From
p-T161-CDK1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 161 (in Homo sapiens)
Coordinate
161
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
XP_003639061.1
,
XP_005618957.1
,
XP_005618958.1
,
XP_013968299.1
,
XP_013968300.1
OpenTargets
ENSG00000170312
Ensembl
ENSCAFP00845004207
,
ENSCAFT00845005291
,
ENSCAFG00845002973
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