Reactome | RNPS1 [cytosol]

RNPS1 [cytosol]

Stable Identifier

R-CFA-159256

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

RNPS1, A0A8I3MQA2

Locations in the PathwayBrowser

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Metabolism of RNA (Canis familiaris)

- Nonsense-Mediated Decay (NMD) (Canis familiaris)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Canis familiaris)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Canis familiaris)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Canis familiaris)
        
        RNPS1 [cytosol] (Canis familiaris)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Canis familiaris)
        
        RNPS1 [cytosol] (Canis familiaris)
    - SMG6 hydrolyzes mRNA with premature termination codon (Canis familiaris)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Canis familiaris)
        
        RNPS1 [cytosol] (Canis familiaris)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Canis familiaris)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Canis familiaris)
        
        RNPS1 [cytosol] (Canis familiaris)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Canis familiaris)
        
        RNPS1 [cytosol] (Canis familiaris)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Canis familiaris)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Canis familiaris)
        
        RNPS1 [cytosol] (Canis familiaris)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Canis familiaris)
        
        RNPS1 [cytosol] (Canis familiaris)
- Processing of Capped Intron-Containing Pre-mRNA (Canis familiaris)
  - Transport of Mature Transcript to Cytoplasm (Canis familiaris)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Canis familiaris)
      - Transport of the export-competent mRNP complex through the NPC (Canis familiaris)
        
        NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol] (Canis familiaris)
        
        EJC [cytosol] (Canis familiaris)
        
        RNPS1 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3MQA2

Gene Names

RNPS1

Reference Genes

BioGPS Gene:479880 RNPS1

ENSEMBL:ENSCAFG00845004488.1

KEGG:cfa:479880 RNPS1

Monarch:479880 RNPS1

NCBI Gene:479880 RNPS1

UCSC:A0A8I3MQA2 RNPS1

Reference Transcript

Other Identifiers

479880

CfaAffx.29652.1.S1_at

GO:0000184

GO:0000381

GO:0003676

GO:0003723

GO:0003730

GO:0005634

GO:0005654

GO:0005737

GO:0006397

GO:0008380

GO:0016071

GO:0016607

GO:0043065

GO:0048025

GO:0061574

Participates

as a component of

Other forms of this molecule

RNPS1 [nucleoplasm]

Inferred From

RNPS1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_537005.1, XP_005621745.1, XP_013970166.1, XP_038396645.1, XP_038396644.1, XP_038525449.1, XP_038525450.1

ENSEMBL

ENSCAFP00845006331, ENSCAFT00845008049, ENSCAFG00845004488