Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Ghost homologue of BRK1 [cytosol]
Stable Identifier
R-CFA-1671645
Type
Genes and Transcripts [GenomeEncodedEntity]
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Innate Immune System (Canis familiaris)
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
Regulation of actin dynamics for phagocytic cup formation (Canis familiaris)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Canis familiaris)
Mother filament:branching complex [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP [plasma membrane] (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP [plasma membrane] (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
ABL phosphorylates WAVEs (Canis familiaris)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
Detachment of WASP/WAVE (Canis familiaris)
Mother filament:branching complex [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP [plasma membrane] (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP [plasma membrane] (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-ERK phosphorylates WAVEs and ABI (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases Activate WASPs and WAVEs (Canis familiaris)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Canis familiaris)
Mother filament:branching complex [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP [plasma membrane] (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP [plasma membrane] (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
ABL phosphorylates WAVEs (Canis familiaris)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
Detachment of WASP/WAVE (Canis familiaris)
Mother filament:branching complex [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP [plasma membrane] (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
WAVE2, WASP, N-WASP [plasma membrane] (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC) (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-ERK phosphorylates WAVEs and ABI (Canis familiaris)
p-Y,S,T-WRC:IRSp53/58:RAC1:GTP:PIP3 [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
p-Y-WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
RHO GTPase cycle (Canis familiaris)
RAC1 GTPase cycle (Canis familiaris)
RAC1 binds effectors at the plasma membrane (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
RAC1:GTP:RAC1 effectors [plasma membrane] (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
RAC2 GTPase cycle (Canis familiaris)
RAC2 binds effectors at the plasma membrane (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
WAVE2 Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
WAVE2 Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
RAC3 GTPase cycle (Canis familiaris)
RAC3 binds effectors at the plasma membrane (Canis familiaris)
RAC3 effectors [cytosol] (Canis familiaris)
WAVE1 Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
WAVE2 Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
RAC3:GTP:RAC3 effectors [plasma membrane] (Canis familiaris)
RAC3 effectors [cytosol] (Canis familiaris)
WAVE1 Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
WAVE2 Regulatory Complex [cytosol] (Canis familiaris)
Ghost homologue of BRK1 [cytosol] (Canis familiaris)
Participates
as a component of
WAVE1 Regulatory Complex [cytosol] (Canis familiaris)
WAVE2 Regulatory Complex [cytosol] (Canis familiaris)
p-Y,S,T-WRC [cytosol] (Canis familiaris)
p-Y-WRC [cytosol] (Canis familiaris)
WAVE Regulatory Complex [cytosol] (Canis familiaris)
Inferred From
BRK1 [cytosol]
(Homo sapiens)
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
