Reactome | GNA13 [plasma membrane]

GNA13 [plasma membrane]

Stable Identifier

R-CFA-167451

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

GNA13, A0A8I3PZN6

Locations in the PathwayBrowser

Expand all

Hemostasis (Canis familiaris)

- Platelet activation, signaling and aggregation (Canis familiaris)
  - Signal amplification (Canis familiaris)
    - Thromboxane signalling through TP receptor (Canis familiaris)
      - Activated TP receptor binds G-protein G13 (Canis familiaris)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (13):GDP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)
        
        TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (13):GDP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)
      - Dissociation of the TP:G13 complex (Canis familiaris)
        
        G-protein alpha (13):GTP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)
        
        TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (13):GTP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)
      - G13 activation by TP receptor (Canis familiaris)
        
        TP receptor:Thromboxane A2:G-protein G13 (active) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (13):GTP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)
        
        TP receptor:Thromboxane A2:G-protein G13 (inactive) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (13):GDP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)
  - Thrombin signalling through proteinase activated receptors (PARs) (Canis familiaris)
    - Thrombin-activated PARs activate G12/13 (Canis familiaris)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Canis familiaris)
        
        G-protein G12/G13 (active) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (13):GTP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)
      - Thrombin activated PAR:G12/13 (inactive) [plasma membrane] (Canis familiaris)
        
        G-protein G12/G13 (inactive) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein G13 (inactive) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (13):GDP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)
    - Thrombin-activated PARs:G12/13 (active) dissociate (Canis familiaris)
      - G-protein alpha (12/13):GTP [plasma membrane] (Canis familiaris)
        
        G-protein alpha (13):GTP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)
      - Thrombin activated PAR:G12/13 (active) [plasma membrane] (Canis familiaris)
        
        G-protein G12/G13 (active) [plasma membrane] (Canis familiaris)
        
        Heterotrimeric G-protein G13 (active) [plasma membrane] (Canis familiaris)
        
        G-protein alpha (13):GTP [plasma membrane] (Canis familiaris)
        
        GNA13 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PZN6

Gene Names

GNA13

Reference Genes

ENSEMBL:ENSCAFG00845028829.1

UCSC:A0A8I3PZN6 GNA13

Other Identifiers

Cfa.15167.1.S1_at

Cfa.15167.2.A1_at

CfaAffx.17340.1.S1_at

GO:0001525

GO:0001569

GO:0001664

GO:0001701

GO:0003824

GO:0003924

GO:0003925

GO:0005525

GO:0005634

GO:0005737

GO:0005829

GO:0007165

GO:0007186

GO:0007188

GO:0007189

GO:0007266

GO:0008217

GO:0008360

GO:0010762

GO:0016787

GO:0019001

GO:0030154

GO:0030168

GO:0031683

GO:0035556

GO:0043226

GO:0048856

GO:0098772

GO:0098794

GO:0150052

Participates

as a candidate of

CDC42 GEFs [cytosol] (Canis familiaris)

as a member of

RAC1 GEFs [cytosol] (Canis familiaris)

as a component of

Inferred From

GNA13 [plasma membrane] (Homo sapiens)

Cross References

ENSEMBL

ENSCAFP00845039931, ENSCAFT00845050935

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