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What is Reactome ?
News
Team
Scientific Advisory Board
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Statistics
Our Logo
License Agreement
Privacy Notice
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Content
Table of Contents
DOIs
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COVID-19 Disease Pathways
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NFKB1 [cytosol]
Stable Identifier
R-CFA-168168
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
NFKB1(1-433), Q6F3J0
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Signaling by the B Cell Receptor (BCR) (Canis familiaris)
Downstream signaling events of B Cell Receptor (BCR) (Canis familiaris)
Activation of NF-kappaB in B cells (Canis familiaris)
Activated IKK phosphorylates I-kappaB (Canis familiaris)
NF-kappa-B p50,p65,c-Rel:IKB [cytosol] (Canis familiaris)
NF-KappaB p50:p50:IKBA [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel:IkB [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:p65:IKB [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Canis familiaris)
NF-KappaB p50:p50:p-IKBA [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel:p-IKB [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:p65:p-IKB [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB translocates from the cytosol to the nucleus (Canis familiaris)
NF-kappaB p50,p65,c-Rel dimer [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
SCF with beta-TrCP1 or beta-TrCP2 binds NF-kappaB:phospho-IkB (Canis familiaris)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Canis familiaris)
NF-KappaB p50:p50:p-IKBA [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel:p-IKB [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:p65:p-IKB [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Canis familiaris)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Canis familiaris)
NF-KappaB p50:p50:p-IKBA [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel:p-IKB [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:p65:p-IKB [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
SCF-beta-TrCP ubiquitinylates IkB (Canis familiaris)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Canis familiaris)
NF-KappaB p50:p50:ub-p-IKBA [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB:p-IkB:SCF-betaTrCP [cytosol] (Canis familiaris)
NF-kappa-B p50,p65,c-Rel:p-IKB [cytosol] (Canis familiaris)
NF-KappaB p50:p50:p-IKBA [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel:p-IKB [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:p65:p-IKB [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Ubiquitinated IkB is degraded (Canis familiaris)
NF-kappaB p50,p65,c-Rel dimer [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Canis familiaris)
NF-KappaB p50:p50:ub-p-IKBA [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Canis familiaris)
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kappaB p50:p65:ub-p-IKB [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
TCR signaling (Canis familiaris)
Downstream TCR signaling (Canis familiaris)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Canis familiaris)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:RELA translocates from the cytosol to the nucleus (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Canis familiaris)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Canis familiaris)
IkB(alpha):NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-1 family signaling (Canis familiaris)
Interleukin-1 signaling (Canis familiaris)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Canis familiaris)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Canis familiaris)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:RELA translocates from the cytosol to the nucleus (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Canis familiaris)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
C-type lectin receptors (CLRs) (Canis familiaris)
CLEC7A (Dectin-1) signaling (Canis familiaris)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Canis familiaris)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:RELA translocates from the cytosol to the nucleus (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Canis familiaris)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Canis familiaris)
IkB(alpha):NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Cytosolic sensors of pathogen-associated DNA (Canis familiaris)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Canis familiaris)
NFkB complex translocates from the cytosol to the nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
ZBP1(DAI) mediated induction of type I IFNs (Canis familiaris)
RIP-mediated NFkB activation via ZBP1 (Canis familiaris)
NFkB complex translocates from the cytosol to the nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Canis familiaris)
TRAF6 mediated NF-kB activation (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated NF-kB activation (Canis familiaris)
26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex (Canis familiaris)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1:RELA translocates from the cytosol to the nucleus (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
beta-TRCP ubiquitinates IkB-alpha in p-S32,33-IkB-alpha:NF-kB complex (Canis familiaris)
K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Canis familiaris)
IkB(alpha):NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p-S32,36-IkB-alpha:NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88-independent TLR4 cascade (Canis familiaris)
TRIF(TICAM1)-mediated TLR4 signaling (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Canis familiaris)
NFkB complex is transported from cytosol to nucleus (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor binds NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Phospho-IKK Complex phosphorylates NFkB inhibitor within the NFkB inhibitor:NFkB complex (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFkB inhibitor:NFkB complex [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454):RELA [cytosol] (Canis familiaris)
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Death Receptor Signalling (Canis familiaris)
p75 NTR receptor-mediated signalling (Canis familiaris)
Regulated proteolysis of p75NTR (Canis familiaris)
p75NTR ICD signals to NF-kB (Canis familiaris)
NF-kB:p75NTR ICD:TRAF6 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
p75NTR signals via NF-kB (Canis familiaris)
NF-kB is activated and signals survival (Canis familiaris)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Canis familiaris)
IkB(alpha):NF-kB complex [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
NF-kB migrates to the nucleus and turns on transcription (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:Q6F3J0
Gene Names
NFKB1
Reference Genes
BioGPS Gene:442859 NFKB1
ENSEMBL:ENSCAFG00030020386
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00030020386 NFKB1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00040022966 NFKB1
KEGG Gene (Canis lupus familiaris):442859 NFKB1
Monarch:442859 NFKB1
NCBI Gene:442859 NFKB1
Reference Transcript
RefSeq:NM_001003344.1 NFKB1
Participates
as a component of
NF-kappaB p50:c-Rel [cytosol] (Canis familiaris)
NF-kappaB p50:p50 [cytosol] (Canis familiaris)
NFKB1(1-433):RELA [cytosol] (Canis familiaris)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA [cytosol] (Canis familiaris)
NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Canis familiaris)
as a member of
NFKB1(1-433), NFKB2(1-454) [cytosol] (Canis familiaris)
Other forms of this molecule
NFKB1 [secretory granule lumen]
NFKB1 [extracellular region]
NFKB1 [specific granule lumen]
NFKB1 [nucleoplasm]
NFKB1 [cytosol]
phospho-NFKB1 [cytosol]
Inferred From
NFKB1(1-433) [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001003344.1
OpenTargets
ENSG00000109320
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