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MAPKs [cytosol]
Stable Identifier
R-CFA-169291
Type
Set [DefinedSet]
Species
Canis familiaris
Compartment
cytosol
Synonyms
MAPK1,MAPK3
Locations in the PathwayBrowser
Expand all
Hemostasis (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
Thrombin signalling through proteinase activated receptors (PARs) (Canis familiaris)
Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Canis familiaris)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
F2R:ARRB1 binds MAPKs, SRC-1 (Canis familiaris)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
F2R:ARRB2 binds MAPKs, SRC-1 (Canis familiaris)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
SRC-1 bound to ARRB2 is not activated (Canis familiaris)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Canis familiaris)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Growth hormone receptor signaling (Canis familiaris)
Lyn activates ERK (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF-independent MAPK1/3 activation (Canis familiaris)
Cytosolic DUSPs dephosphorylate MAPKs (Canis familiaris)
MAPK monomers and dimers [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
Dual mechanism MAPK inhibitors bind MAPKs (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
IL17RD binds p-2S MAP2Ks and MAPKs (Canis familiaris)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex [endosome membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAP2Ks and MAPKs bind to the activated RAF complex (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Canis familiaris)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
RAF phosphorylates MAP2K dimer (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex [endosome membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
Negative regulation of MAPK pathway (Canis familiaris)
Cytosolic DUSPs dephosphorylate MAPKs (Canis familiaris)
MAPK monomers and dimers [cytosol] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
Signalling to ERKs (Canis familiaris)
Prolonged ERK activation events (Canis familiaris)
Frs2-mediated activation (Canis familiaris)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Canis familiaris)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Canis familiaris)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Canis familiaris)
MAPKs [cytosol] (Canis familiaris)
Participants
members
MAPK1 [cytosol]
(Canis familiaris)
MAPK3 [cytosol]
(Canis familiaris)
Participates
as an input of
Lyn activates ERK (Canis familiaris)
F2R:ARRB1 binds MAPKs, SRC-1 (Canis familiaris)
F2R:ARRB2 binds MAPKs, SRC-1 (Canis familiaris)
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Canis familiaris)
IL17RD binds p-2S MAP2Ks and MAPKs (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Canis familiaris)
MAP2Ks and MAPKs bind to the activated RAF complex (Canis familiaris)
as a component of
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Canis familiaris)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Canis familiaris)
WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex [endosome membrane] (Canis familiaris)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Canis familiaris)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
as a member of
MAPK monomers and dimers [cytosol] (Canis familiaris)
Inferred From
MAPKs [cytosol]
(Homo sapiens)
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