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phosphorylated anaphase promoting complex (APC/C) [cytosol]
Stable Identifier
R-CFA-174191
Type
Complex
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
Mitotic Spindle Checkpoint (Canis familiaris)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Canis familiaris)
Inactivation of APC/C via direct inhibition of the APC/C complex (Canis familiaris)
Binding of the MCC complex to the APC/C complex (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Separation of Sister Chromatids (Canis familiaris)
Association of Securin with Cdc20:APC/C complex (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
CDC20:p-APC/C:PTTG1 [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Degradation of multiubiquitinated Securin (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Canis familiaris)
CDC20:p-APC/C:PTTG1 [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Regulation of mitotic cell cycle (Canis familiaris)
APC/C-mediated degradation of cell cycle proteins (Canis familiaris)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Canis familiaris)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Canis familiaris)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Degradation of multiubiquitinated cell cycle proteins (Canis familiaris)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Canis familiaris)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Canis familiaris)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Canis familiaris)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Canis familiaris)
APC/C:Cdc20 mediated degradation of mitotic proteins (Canis familiaris)
APC/C:Cdc20 mediated degradation of Cyclin B (Canis familiaris)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Degradation of multiubiquitinated Cyclin B (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Canis familiaris)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Canis familiaris)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Canis familiaris)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
APC/C:Cdc20 mediated degradation of Securin (Canis familiaris)
Association of Securin with Cdc20:APC/C complex (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
CDC20:p-APC/C:PTTG1 [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Degradation of multiubiquitinated Securin (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Canis familiaris)
CDC20:p-APC/C:PTTG1 [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Canis familiaris)
APC-Cdc20 mediated degradation of Nek2A (Canis familiaris)
Association of Nek2A with MCC:APC/C (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Nek2A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Degradation of multiubiquitinated Nek2A (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Multiubiquitinated Nek2A [cytosol] (Canis familiaris)
Nek2A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Multiubiquitination of Nek2A (Canis familiaris)
Multiubiquitinated Nek2A [cytosol] (Canis familiaris)
Nek2A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Nek2A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Canis familiaris)
Association of Cyclin A with the APC/C (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Degradation multiubiquitinated Cyclin A (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Canis familiaris)
Association of Cdh1 with the APC/C (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Dissociation of Cdc20 from APC/C complex (Canis familiaris)
CDC20:p-APC/C [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
Regulation of APC/C activators between G1/S and early anaphase (Canis familiaris)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Canis familiaris)
Inactivation of APC/C via direct inhibition of the APC/C complex (Canis familiaris)
Binding of the MCC complex to the APC/C complex (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
S Phase (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
CDK-mediated phosphorylation and removal of Cdc6 (Canis familiaris)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
DNA Replication (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
CDK-mediated phosphorylation and removal of Cdc6 (Canis familiaris)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ANAPC1 [cytosol]
(Canis familiaris)
ANAPC10 [cytosol]
(Canis familiaris)
ANAPC11 [cytosol]
(Canis familiaris)
ANAPC15 [cytosol]
(Canis familiaris)
ANAPC16 [cytosol]
(Canis familiaris)
ANAPC4 [cytosol]
(Canis familiaris)
ANAPC5 [cytosol]
(Canis familiaris)
ANAPC7 [cytosol]
(Canis familiaris)
CDC16 [cytosol]
(Canis familiaris)
CDC26 [cytosol]
(Canis familiaris)
CDC27 [cytosol]
(Canis familiaris)
GFRA3 [cytosol]
(Canis familiaris)
TMEM210 [cytosol]
(Canis familiaris)
UBE2C [cytosol]
(Canis familiaris)
UBE2D1 [cytosol]
(Canis familiaris)
UBE2E1 [cytosol]
(Canis familiaris)
UBE2S [cytosol]
(Canis familiaris)
Participates
as an input of
Association of Cdh1 with the APC/C (Canis familiaris)
Binding of the MCC complex to the APC/C complex (Canis familiaris)
as an output of
Dissociation of Cdc20 from APC/C complex (Canis familiaris)
as a component of
CDC20:p-APC/C [cytosol] (Canis familiaris)
phospho-APC/C:Cdh1 complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Inferred From
phosphorylated anaphase promoting complex (APC/C) [cytosol]
(Homo sapiens)
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