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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
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Digital Preservation
Contact us
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Table of Contents
DOIs
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Docs
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How do I search ?
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GAB1 [cytosol]
Stable Identifier
R-CFA-179795
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
GAB1, A0A8I3NXI8
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
RET signaling (Canis familiaris)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Canis familiaris)
GAB1,GAB2 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Canis familiaris)
2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Canis familiaris)
GAB1,GAB2 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GAB1,GAB2 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
Negative regulation of the PI3K/AKT network (Canis familiaris)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
BDNF,NTF4:p-5Y-NTRK2:GRB2:GAB1:PIK3CA:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activator:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
BDNF,NTF4:p-5Y-NTRK2:GRB2:GAB1:PIK3CA:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by Erythropoietin (Canis familiaris)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Canis familiaris)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Canis familiaris)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:GAB1 [plasma membrane] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Canis familiaris)
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:GAB1 [plasma membrane] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by EGFR (Canis familiaris)
GAB1 signalosome (Canis familiaris)
Binding of GRB2 to GAB1 (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GAB1 binds phosphatidylinositol-3,4,5-trisphosphate (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIP3 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GAB1 phosphorylation by EGFR kinase (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Canis familiaris)
GRB2:GAB1,GRB2:GAB1:PIP3 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIP3 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1 binds to phosphorylated EGFR (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:GRB2:GAB1 [plasma membrane] (Canis familiaris)
GRB2:GAB1,GRB2:GAB1:PIP3 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIP3 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1,GRB2:GAB1:PIP3 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIP3 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by ERBB2 (Canis familiaris)
PI3K events in ERBB2 signaling (Canis familiaris)
Binding of GRB2:GAB1 to p-ERBB2:p-EGFR (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Binding of PI3K to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
EGF:p-EGFR:p-ERBB2:GRB2:GAB1 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by FGFR (Canis familiaris)
Signaling by FGFR1 (Canis familiaris)
Downstream signaling of activated FGFR1 (Canis familiaris)
PI-3K cascade:FGFR1 (Canis familiaris)
Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR1:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Canis familiaris)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR1:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by FGFR2 (Canis familiaris)
Downstream signaling of activated FGFR2 (Canis familiaris)
PI-3K cascade:FGFR2 (Canis familiaris)
Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by FGFR3 (Canis familiaris)
Downstream signaling of activated FGFR3 (Canis familiaris)
PI-3K cascade:FGFR3 (Canis familiaris)
Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1 binds PIK3CA (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by FGFR4 (Canis familiaris)
Downstream signaling of activated FGFR4 (Canis familiaris)
PI-3K cascade:FGFR4 (Canis familiaris)
Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11:GRB2:GAB1:PIK3R1binds PIK3CA (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
GRB2:GAB1:PIK3R1 [cytosol] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by Insulin receptor (Canis familiaris)
Insulin receptor signalling cascade (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by MET (Canis familiaris)
MET activates PI3K/AKT signaling (Canis familiaris)
Activated MET binds GAB1 (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Activated MET binds GAB1 and GRB2 (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
MET phosphorylates GAB1 (Canis familiaris)
HGF:p-4Y-MET dimer:GAB1,HGF:p-4Y-MET dimer:GRB2:GAB1 [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Canis familiaris)
IGF1R signaling cascade (Canis familiaris)
IRS-related events triggered by IGF1R (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes [cytosol] (Canis familiaris)
Activated FGFR bound to PI3K [cytosol] (Canis familiaris)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Canis familiaris)
GAB1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3NXI8
Gene Names
GAB1
Reference Genes
ENSEMBL:ENSCAFG00845018786.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845018786.1 GAB1
Other Identifiers
483808
Cfa.1615.1.S1_at
Cfa.19271.1.S1_s_at
Cfa.19430.1.S1_at
CfaAffx.6359.1.S1_s_at
GO:0001525
GO:0005911
GO:0023052
GO:0038084
GO:0045766
GO:0048856
GO:0048870
GO:0090668
Participates
as an input of
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 binds GAB1 (Canis familiaris)
Activated MET binds GAB1 and GRB2 (Canis familiaris)
Activated MET binds GAB1 (Canis familiaris)
Binding of GRB2 to GAB1 (Canis familiaris)
as a component of
EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:GAB1 [plasma membrane] (Canis familiaris)
GRB2 and GAB1 bound to activated FGFR and FRS2-alpha [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET dimer:GRB2-1:GAB1 [plasma membrane] (Canis familiaris)
HGF:p-4Y-MET dimer:GAB1 [plasma membrane] (Canis familiaris)
GRB2:GAB1 [cytosol] (Canis familiaris)
as a member of
GAB1,GAB2 [cytosol] (Canis familiaris)
Other forms of this molecule
phospho-GAB1 [cytosol]
phospho-GAB1 [cytosol]
phospho-GAB1 [cytosol]
Inferred From
GAB1 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000109458
Ensembl
ENSCAFG00845018786
,
ENSCAFT00845033313
,
ENSCAFP00845026075
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