Reactome | GRB2:GAB1:PIK3R1 [cytosol]

GRB2:GAB1:PIK3R1 [cytosol]

Stable Identifier

R-CFA-179864

Type

Complex

Species

Canis familiaris

Compartment

cytosol

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

GRB2:GAB1 [cytosol] (Canis familiaris)
PIK3R1 [cytosol] (Canis familiaris)

Participates

as an input of

Activated FGFR4:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)
Activated FGFR1:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR4:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR1:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)
Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)
Activated FGFR3:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Canis familiaris)
Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Canis familiaris)

as a component of

Activated FGFR4:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR4:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR1:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)
Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Canis familiaris)

as an output of

Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 (Canis familiaris)

Inferred From

GRB2:GAB1:PIK3R1 [cytosol] (Homo sapiens)