Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
AP2B1 [cytosol]
Stable Identifier
R-CFA-182166
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
A0A5F4CPQ9
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
EPH-Ephrin signaling (Canis familiaris)
EPH-ephrin mediated repulsion of cells (Canis familiaris)
Clathrin internalises EPH:EFN complexes (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
EPHB:EFNB:F-actin:AP-2:Clathrrin:Dynamin [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by WNT (Canis familiaris)
Beta-catenin independent WNT signaling (Canis familiaris)
PCP/CE pathway (Canis familiaris)
WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (Canis familiaris)
FZD2, FZD5 and ROR2 are internalized in a WNT5A and clathrin-dependent manner (Canis familiaris)
clathrin:AP-2 [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
WNT5A-dependent internalization of FZD4 (Canis familiaris)
WNT5A:FZD4 is endocytosed (Canis familiaris)
WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane] (Canis familiaris)
clathrin:AP-2 [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-DVL2 recruits AP-2 and beta-arrestin 2 to promote clathrin-mediated endocytosis (Canis familiaris)
WNT5A:FZD4:p-DVL2:ARRB2:AP-2:clathrin [plasma membrane] (Canis familiaris)
clathrin:AP-2 [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
clathrin:AP-2 [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Clathrin-mediated endocytosis (Canis familiaris)
AAK1 phosphorylates AP-2 mu subunit at T156 (Canis familiaris)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Canis familiaris)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
BAR domain proteins recruit dynamin (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Cargo recognition for clathrin-mediated endocytosis (Canis familiaris)
AP-2 directly binds some endocytic cargo (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
AP2:chlorpromazine [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
AP2 binds chlorpromazine (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
AP2:chlorpromazine [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
ARBB recruits GPCRs into clathrin-coated pits (Canis familiaris)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Clathrin recruits PIK3C2A (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Clathrin recruits auxilins to the clathrin-coated vesicle (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Endophilins recruit synaptojanins to the clathrin-coated pit (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
F- and N- BAR domain proteins bind the clathrin-coated pit (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
Initial binding of AP-2 and clathrin to PI(4,5)P2 (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
RAB5 and GAPVD1 bind AP-2 (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2:cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Canis familiaris)
Clathrin-coated vesicle [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
SNX9 recruits components of the actin polymerizing machinery (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Canis familiaris)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Canis familiaris)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Canis familiaris)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Canis familiaris)
CLASP proteins:cargo [plasma membrane] (Canis familiaris)
AP-2:cargo [plasma membrane] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP2B1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A5F4CPQ9
Reference Genes
ENSEMBL:ENSCAFG00000018246
Participates
as a component of
p-T156 AP-2 Complex [cytosol] (Canis familiaris)
AP-2 Complex [cytosol] (Canis familiaris)
Other forms of this molecule
AP2B1 [endolysosome membrane]
AP2B1-1 [endocytic vesicle membrane]
AP2B1 [plasma membrane]
AP2B1 [clathrin-coated endocytic vesicle membrane]
Inferred From
AP2B1 [cytosol]
(Homo sapiens)
Cross References
VGNC
37960
© 2022
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
