Reactome | TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-CFA-1911531

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

E2RGZ5

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Canis familiaris)

- Post-translational protein modification (Canis familiaris)
  - Asparagine N-linked glycosylation (Canis familiaris)
    - Transport to the Golgi and subsequent modification (Canis familiaris)
      - ER to Golgi Anterograde Transport (Canis familiaris)
        
        COPI-mediated anterograde transport (Canis familiaris)
        
        ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Canis familiaris)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        p24 dimers [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2 dimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        p24 dimers [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2 dimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        ARFGAPs stimulate ARF GTPase activity (Canis familiaris)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        p24 dimers [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2 dimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)
        
        TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:E2RGZ5

Reference Genes

ENSEMBL:ENSCAFG00000007468

Other Identifiers

100687986

Cfa.10752.1.S1_at

CfaAffx.12074.1.S1_s_at

Participates

as a component of

TMED2 dimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Canis familiaris)

This entity regulates

Negatively

Mature NOTCH heterodimer traffics to the plasma membrane (Canis familiaris)

Other forms of this molecule

TMED2 [endoplasmic reticulum membrane]

TMED2 [transport vesicle]

TMED2 [Golgi membrane]

Inferred From

TMED2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Cross References

Ensembl

ENSCAFG00845017382, ENSCAFT00845030818, ENSCAFP00845024160

VGNC

57417