Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
CREBBP [nucleoplasm]
Stable Identifier
R-CFA-193545
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
CREBBP, A0A8I3MJJ8
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Cytoprotection by HMOX1 (Canis familiaris)
Fatty acid ligands activate PPARA (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
PPARA:RXRA Coactivator complex [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
KEAP1-NFE2L2 pathway (Canis familiaris)
Nuclear events mediated by NFE2L2 (Canis familiaris)
CREBBP, EP300 acetylates NFE2L2 (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm] (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
p-NFE2L2:CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
NFE2L2 binds CREBBP,EP300 (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
p-NFE2L2:CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Cellular response to heat stress (Canis familiaris)
HSF1-dependent transactivation (Canis familiaris)
Attenuation phase (Canis familiaris)
HSF1 acetylation at Lys80 (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Cellular response to hypoxia (Canis familiaris)
Regulation of gene expression by Hypoxia-inducible Factor (Canis familiaris)
Formation of HIF:CBP:p300 complex at promoters (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
HIF:CBP:p300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Developmental Biology (Canis familiaris)
MITF-M-regulated melanocyte development (Canis familiaris)
Transcriptional and post-translational regulation of MITF-M expression and activity (Canis familiaris)
CREBBP acetylates HINT1 dimer (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
HINT1 binds MITF-M (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
FOXO-mediated transcription (Canis familiaris)
Regulation of FOXO transcriptional activity by acetylation (Canis familiaris)
CREBBP binds FOXO1 (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
FOXO1:CREBBP [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Transcriptional regulation by RUNX1 (Canis familiaris)
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells (Canis familiaris)
RUNX1:CBFB binds CREBBP (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:CREBBP [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Transcriptional regulation by RUNX3 (Canis familiaris)
RUNX3 regulates NOTCH signaling (Canis familiaris)
RUNX3 binds the NOTCH1 coactivator complex (Canis familiaris)
NOTCH1 Coactivator Complex [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
RUNX3:NOTCH1 Coactivator Complex [nucleoplasm] (Canis familiaris)
NOTCH1 Coactivator Complex [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Canis familiaris)
Activation of the TFAP2 (AP-2) family of transcription factors (Canis familiaris)
TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
TFAP2 homo- and heterodimers:CITED2,CITED4,(CITED1):EP300:CREBBP [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Immune System (Canis familiaris)
Innate Immune System (Canis familiaris)
C-type lectin receptors (CLRs) (Canis familiaris)
CD209 (DC-SIGN) signaling (Canis familiaris)
CBP and p300 binds NF-kB complex (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
p300 acetylates RELA subunit (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
NFKB1:p-S276,5AcK-RELA:p300/CBP [nucleoplasm] (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Cytosolic sensors of pathogen-associated DNA (Canis familiaris)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Canis familiaris)
Beta-catenin enhances association of IRF3 with CBP/p300 (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
beta-catenin:IRF3:p300 [nucleoplasm] (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Regulation of lipid metabolism by PPARalpha (Canis familiaris)
Fatty acid ligands activate PPARA (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
PPARA:RXRA Coactivator complex [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Estrogen-dependent gene expression (Canis familiaris)
GREB1 binds ESR1:ESTG and co-activators (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
GREB1:ESR1:ESTG:EP300:CREBBP [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
Signaling by WNT (Canis familiaris)
TCF dependent signaling in response to WNT (Canis familiaris)
Formation of the beta-catenin:TCF transactivating complex (Canis familiaris)
Beta-catenin recruits CBP/p300 (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] (Canis familiaris)
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
CREBBP [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3MJJ8
Gene Names
CREBBP
Reference Genes
ENSEMBL:ENSCAFG00845001617.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845001617.1 CREBBP
Other Identifiers
479866
Cfa.8999.1.A1_at
CfaAffx.29383.1.S1_at
CfaAffx.29386.1.S1_s_at
GO:0000122
GO:0000123
GO:0000785
GO:0001223
GO:0002039
GO:0003677
GO:0003682
GO:0003684
GO:0003712
GO:0003713
GO:0003714
GO:0003824
GO:0004402
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0008270
GO:0016407
GO:0016479
GO:0016573
GO:0016604
GO:0016740
GO:0016746
GO:0023052
GO:0030511
GO:0031648
GO:0031669
GO:0032991
GO:0034644
GO:0036211
GO:0038061
GO:0043226
GO:0043229
GO:0043426
GO:0045893
GO:0045944
GO:0046872
GO:0048511
GO:0050896
GO:0061629
GO:0061733
GO:0140096
GO:0140110
GO:0140297
GO:1900182
Participates
as an input of
GREB1 binds ESR1:ESTG and co-activators (Canis familiaris)
CREBBP binds FOXO1 (Canis familiaris)
RUNX1:CBFB binds CREBBP (Canis familiaris)
TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Canis familiaris)
Formation of HIF:CBP:p300 complex at promoters (Canis familiaris)
as a component of
GREB1:ESR1:ESTG:EP300:CREBBP [nucleoplasm] (Canis familiaris)
FOXO1:CREBBP [nucleoplasm] (Canis familiaris)
RUNX1:CBFB:CREBBP [nucleoplasm] (Canis familiaris)
TFAP2 homo- and heterodimers:CITED2,CITED4,(CITED1):EP300:CREBBP [nucleoplasm] (Canis familiaris)
HIF:CBP:p300 [nucleoplasm] (Canis familiaris)
NOTCH1 Coactivator Complex [nucleoplasm] (Canis familiaris)
as a member of
CREBBP,EP300 [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
This entity regulates
Negatively
HINT1 binds MITF-M
(Canis familiaris)
Inferred From
CREBBP [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000005339
Ensembl
ENSCAFT00845002858
,
ENSCAFG00845001617
,
ENSCAFP00845002277
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text