Reactome | ATF1 [nucleoplasm]

ATF1 [nucleoplasm]

Stable Identifier

R-CFA-199900

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

ATF1, A0A5F4C757

Locations in the PathwayBrowser

Expand all

Immune System (Canis familiaris)

- Cytokine Signaling in Immune system (Canis familiaris)
  - Signaling by Interleukins (Canis familiaris)
    - Interleukin-17 signaling (Canis familiaris)
      - MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)
- Innate Immune System (Canis familiaris)
  - Toll-like Receptor Cascades (Canis familiaris)
    - Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
      - MyD88 cascade initiated on plasma membrane (Canis familiaris)
        
        MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)
    - Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
      - Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
        
        MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)
      - Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
        
        MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)
    - Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
      - MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)
    - Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
      - MyD88-independent TLR4 cascade (Canis familiaris)
        
        TRIF(TICAM1)-mediated TLR4 signaling (Canis familiaris)
        
        MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
        
        MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)
    - Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
      - MyD88 cascade initiated on plasma membrane (Canis familiaris)
        
        MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
      - MyD88 dependent cascade initiated on endosome (Canis familiaris)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
        
        MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)
    - Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
      - MyD88 dependent cascade initiated on endosome (Canis familiaris)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
        
        MAP kinase activation (Canis familiaris)
        
        MAPK targets/ Nuclear events mediated by MAP kinases (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)

Signal Transduction (Canis familiaris)

- Signaling by Receptor Tyrosine Kinases (Canis familiaris)
  - Signaling by NTRKs (Canis familiaris)
    - Signaling by NTRK1 (TRKA) (Canis familiaris)
      - Nuclear Events (kinase and transcription factor activation) (Canis familiaris)
        
        CREB phosphorylation (Canis familiaris)
        
        MSK1 activates ATF1 (Canis familiaris)
        
        ATF1 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A5F4C757

Gene Names

ATF1

Reference Genes

ENSEMBL:ENSCAFG00000007928

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000007928 ATF1

Other Identifiers

486545

608553

CfaAffx.12715.1.S1_s_at

GO:0003674

GO:0003677

GO:0003700

GO:0004252

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0006355

GO:0006357

GO:0006508

GO:0008150

GO:0008233

GO:0009058

GO:0034641

GO:0043226

GO:0043565

GO:0046982

Participates

as an input of

MSK1 activates ATF1 (Canis familiaris)

Other forms of this molecule

phospho-ATF1 [nucleoplasm]

Inferred From

ATF1 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000123268

Ensembl

ENSCAFG00000007928, ENSCAFP00000050106, ENSCAFT00000078821

VGNC

38207

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