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p-T,p-S-AKT [cytosol]
Stable Identifier
R-CFA-202074
Type
Set [CandidateSet]
Species
Canis familiaris
Compartment
cytosol
Synonyms
Active AKT
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Mitotic G1 phase and G1/S transition (Canis familiaris)
G1/S Transition (Canis familiaris)
Cyclin E associated events during G1/S transition (Canis familiaris)
AKT phosphorylates p21Cip1 and p27Kip1 (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
S Phase (Canis familiaris)
Cyclin A:Cdk2-associated events at S phase entry (Canis familiaris)
AKT phosphorylates p21Cip1 and p27Kip1 (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
KEAP1-NFE2L2 pathway (Canis familiaris)
NFE2L2 translocates from cytosol to nucleoplasm (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
Regulation of TP53 Activity (Canis familiaris)
Regulation of TP53 Expression and Degradation (Canis familiaris)
Regulation of TP53 Degradation (Canis familiaris)
AKT phosphorylates MDM2 (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
AKT phosphorylates TSC2, inhibiting it (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Costimulation by the CD28 family (Canis familiaris)
CD28 co-stimulation (Canis familiaris)
CD28 dependent PI3K/Akt signaling (Canis familiaris)
AKT interacts and phosphorylates Cot (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
CTLA4 inhibitory signaling (Canis familiaris)
Dephosphorylation of AKT by PP2A (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
PIP3 activates AKT signaling (Canis familiaris)
AKT phosphorylates targets in the cytosol (Canis familiaris)
AKT phosphorylates AKT1S1 (PRAS40) (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
AKT phosphorylates IKKalpha (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
AKT phosphorylates MDM2 (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
AKT phosphorylates MKRN1 (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
AKT phosphorylates TSC2, inhibiting it (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
AKT phosphorylates caspase-9 (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
AKT phosphorylates p21Cip1 and p27Kip1 (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
Negative regulation of the PI3K/AKT network (Canis familiaris)
PHLPP dephosphorylates S473 in AKT (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
PTEN Regulation (Canis familiaris)
Regulation of PTEN stability and activity (Canis familiaris)
AKT phosphorylates MKRN1 (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by ERBB2 (Canis familiaris)
Downregulation of ERBB2 signaling (Canis familiaris)
Downregulation of ERBB2:ERBB3 signaling (Canis familiaris)
Phosphorylation of USP8 by P-AKT (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Rab regulation of trafficking (Canis familiaris)
RAB GEFs exchange GTP for GDP on RABs (Canis familiaris)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Canis familiaris)
p-T,p-S-AKT [cytosol] (Canis familiaris)
Participants
members
phospho-AKT1 [cytosol]
(Canis familiaris)
candidates
phospho-AKT2 [cytosol]
(Canis familiaris)
phospho-AKT3 [cytosol]
(Canis familiaris)
Participates
as an input of
Dephosphorylation of AKT by PP2A (Canis familiaris)
PHLPP dephosphorylates S473 in AKT (Canis familiaris)
This entity regulates
Positively
NFE2L2 translocates from cytosol to nucleoplasm
(Canis familiaris)
Inferred From
p-T,p-S-AKT [cytosol]
(Homo sapiens)
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