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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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UBE2N:UBE2V1 [cytosol]
Stable Identifier
R-CFA-202463
Type
Complex
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Canis familiaris)
Macroautophagy (Canis familiaris)
Selective autophagy (Canis familiaris)
Aggrephagy (Canis familiaris)
Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Canis familiaris)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Canis familiaris)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
Ub:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
Ub:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Parkin binds Ub:UBE2N:UBE2V1 (Canis familiaris)
Ub:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
Ub:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Parkin transfers Ub to misfolded proteins (Canis familiaris)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Canis familiaris)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
Ub:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
PolyUb:misfolded proteins dissociate from PRKN:UBE2N:UBE2V1 (Canis familiaris)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Canis familiaris)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Mitophagy (Canis familiaris)
PINK1-PRKN Mediated Mitophagy (Canis familiaris)
PRKN ubiquitinates MOM substrates (Canis familiaris)
UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
TCR signaling (Canis familiaris)
Downstream TCR signaling (Canis familiaris)
Auto-ubiquitination of TRAF6 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Ubiquitination of NEMO by TRAF6 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-1 family signaling (Canis familiaris)
Interleukin-1 signaling (Canis familiaris)
K63polyUb-IRAK1 dissociates (Canis familiaris)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Pellino ubiquitinates IRAK1 (Canis familiaris)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1 is activated within the TAK1 complex (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TRAF6 is K63 poly-ubiquitinated (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Interleukin-17 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
C-type lectin receptors (CLRs) (Canis familiaris)
CLEC7A (Dectin-1) signaling (Canis familiaris)
K63polyUb-TRAF6 ubiquitinates TAK1 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TRAF6 oligomer autoubiquitinates (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Ubiquitination of NEMO by TRAF6 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated NF-kB activation (Canis familiaris)
Auto-ubiquitination of TRAF6 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Ubiquitination of NEMO by TRAF6 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Canis familiaris)
NOD1/2 Signaling Pathway (Canis familiaris)
RIP2 induces K63-linked ubiquitination of NEMO (Canis familiaris)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
RIP2 is K63 polyubiquitinated (Canis familiaris)
RIP2 ubiquitin ligases [cytosol] (Canis familiaris)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88-independent TLR4 cascade (Canis familiaris)
TRIF (TICAM1)-mediated TLR4 signaling (Canis familiaris)
IKK complex recruitment mediated by RIP1 (Canis familiaris)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Canis familiaris)
RIP1 ubiqutin ligases [cytosol] (Canis familiaris)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
K63pUb-TRAF6:TAK1 complexes [cytosol] (Canis familiaris)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1 [cytosol] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
LOC119881719 [cytosol]
(Canis familiaris)
UBE2N [cytosol]
(Canis familiaris)
Participates
as an output of
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Canis familiaris)
UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 (Canis familiaris)
K63polyUb-IRAK1 dissociates (Canis familiaris)
TRAF6 oligomer autoubiquitinates (Canis familiaris)
K63polyUb-TRAF6 ubiquitinates TAK1 (Canis familiaris)
Auto-ubiquitination of TRAF6 (Canis familiaris)
Ubiquitination of NEMO by TRAF6 (Canis familiaris)
Auto-ubiquitination of TRAF6 (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
as an input of
Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation
(Canis familiaris)
TRAF6 oligomer autoubiquitinates (Canis familiaris)
K63polyUb-TRAF6 ubiquitinates TAK1 (Canis familiaris)
Auto-ubiquitination of TRAF6 (Canis familiaris)
Ubiquitination of NEMO by TRAF6 (Canis familiaris)
Auto-ubiquitination of TRAF6 (Canis familiaris)
Ubiquitination of IKBKG by TRAF6 (Canis familiaris)
Pellino ubiquitinates hp-IRAK1 (Canis familiaris)
as a component of
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Canis familiaris)
TRAF6 E3/E2 ubiquitin ligase complex [cytosol] (Canis familiaris)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Canis familiaris)
Ub:UBE2N:UBE2V1 [cytosol] (Canis familiaris)
UBE2N:UBE2V1:PRKN [cytosol] (Canis familiaris)
as a member of
UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] (Canis familiaris)
Inferred From
UBE2N:UBE2V1 [cytosol]
(Homo sapiens)
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