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YWHAZ [cytosol]
Stable Identifier
R-CFA-206099
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
YWHAZ, A0A8I3Q4Y8
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
G2/M Checkpoints (Canis familiaris)
G2/M DNA damage checkpoint (Canis familiaris)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Canis familiaris)
Association of p-S216-CDC25C with 14-3-3 proteins (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
FOXO-mediated transcription (Canis familiaris)
Regulation of localization of FOXO transcription factors (Canis familiaris)
14-3-3 proteins bind AKT-phosphorylated FOXO1 (Canis familiaris)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
p-T24,S256,S319-FOXO1:YWHAZ,YWHAQ,YWHAG,YWHAB [cytosol] (Canis familiaris)
YWHAZ dimer,YWHAQ dimer,YWHAG dimer,YWHAB dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
14-3-3 proteins bind AKT-phosphorylated FOXO3 (Canis familiaris)
YWHAZ dimer,YWHAQ dimer,SFN dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
p-T32,S253,S315-FOXO3:YWHAZ,YWHAQ,SFN [cytosol] (Canis familiaris)
YWHAZ dimer,YWHAQ dimer,SFN dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
14-3-3 proteins bind AKT-phosphorylated FOXO4 (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
p-T32,S197,S262-FOXO4:YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
DDIT4 binds 14-3-3 dimer (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
DDIT4:14-3-3 dimer [cytosol] (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
p-S939,T1462-TSC2 binding to 14-3-3 dimer is negatively regulated by DDIT4 (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
DDIT4:14-3-3 dimer [cytosol] (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
p-S939,T1462-TSC2:14-3-3 dimer [cytosol] (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Hemostasis (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
GP1b-IX-V activation signalling (Canis familiaris)
14-3-3-zeta binds Raf1 (Canis familiaris)
14-3-3-zeta:Raf1 [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Rap1 signalling (Canis familiaris)
14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Canis familiaris)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Rap1 signal termination by Rap1GAPs (Canis familiaris)
RAP1GAP2:14-3-3beta, zeta [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Canis familiaris)
14-3-3 zeta binding allows recruitment of PI3K (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta:p85-containing Class 1A PI3Ks [plasma membrane] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
p-S585-IL3RB binds 14-3-3 proteins (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Programmed Cell Death (Canis familiaris)
Apoptosis (Canis familiaris)
Intrinsic Pathway for Apoptosis (Canis familiaris)
Activation of BH3-only proteins (Canis familiaris)
Activation of BAD and translocation to mitochondria (Canis familiaris)
Activation of BAD by calcineurin (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Sequestration of BAD protein by 14-3-3 (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
14-3-3 proteins:p-S99-BAD complex [cytosol] (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases activate PKNs (Canis familiaris)
Association of p-S216-CDC25C with 14-3-3 proteins (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
p-S216-CDC25C:14-3-3 protein complex [cytosol] (Canis familiaris)
14-3-3 dimer [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
Signaling by WNT (Canis familiaris)
TCF dependent signaling in response to WNT (Canis familiaris)
Deactivation of the beta-catenin transactivating complex (Canis familiaris)
YWHAZ and XPO1 mediate the nuclear export of beta-catenin (Canis familiaris)
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [cytosol] (Canis familiaris)
YWHAZ [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3Q4Y8
Gene Names
YWHAZ
Reference Genes
ENSEMBL:ENSCAFG00845028920.1
UCSC:A0A8I3Q4Y8 YWHAZ
Other Identifiers
475864
Cfa.10240.1.S1_at
Cfa.18430.1.S1_at
Cfa.7005.1.A1_at
CfaAffx.9531.1.S1_s_at
GO:0005737
GO:0007165
Participates
as an input of
14-3-3 proteins beta and zeta bind and inhibit Rap1Gap2 (Canis familiaris)
p-S585-IL3RB binds 14-3-3 proteins (Canis familiaris)
as a component of
RAP1GAP2:14-3-3beta, zeta [cytosol] (Canis familiaris)
High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(S589)-Bc:14-3-3 zeta [plasma membrane] (Canis familiaris)
XPO1:YWHAZ:p-S20-CBY1:CTNNB1 [cytosol] (Canis familiaris)
YWHAZ dimer [cytosol] (Canis familiaris)
Other forms of this molecule
YWHAZ [nucleoplasm]
Inferred From
14-3-3 beta, zeta [cytosol]
(Homo sapiens)
YWHAZ [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSCAFG00845028920
,
ENSCAFT00845051161
,
ENSCAFP00845040119
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