Reactome | GPC2 [plasma membrane]

GPC2 [plasma membrane]

Stable Identifier

R-CFA-2076624

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

HS(5)-GPC2, E2RAS0

Locations in the PathwayBrowser

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Metabolism (Canis familiaris)

- Metabolism of carbohydrates (Canis familiaris)
  - Glycosaminoglycan metabolism (Canis familiaris)
    - Heparan sulfate/heparin (HS-GAG) metabolism (Canis familiaris)
      - HS-GAG biosynthesis (Canis familiaris)
        
        Some HSPGs are secreted to the plasma membrane (Canis familiaris)
        
        HSPGs [plasma membrane] (Canis familiaris)
        
        HS(5)-PGs [plasma membrane] (Canis familiaris)
        
        GPC2 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:E2RAS0

Gene Names

GPC2

Reference Genes

ENSEMBL:ENSCAFG00000014535

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000014535 GPC2

Other Identifiers

608542

CfaAffx.22417.1.S1_at

GO:0005575

GO:0005576

GO:0005622

GO:0005737

GO:0005783

GO:0005886

GO:0007165

GO:0008150

GO:0009966

GO:0016020

GO:0031012

GO:0031225

GO:0043226

GO:0046658

GO:0062023

Participates

as a member of

HS(5)-PGs [plasma membrane] (Canis familiaris)

Other forms of this molecule

GPC2 [plasma membrane]

GPC2 [Golgi lumen]

GPC2 [lysosomal lumen]

Inferred From

HS(5)-GPC2 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-xylosyl-L-serine (ChEBI:63661) at unknown position

Modification

beta-D-IdoA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS3S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group

PsiMod Name

O-xylosyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O3-xylosylserine.

Cross References

OpenTargets

ENSG00000213420

Ensembl

ENSCAFT00000023088, ENSCAFG00000014535, ENSCAFP00000021439

VGNC

41372

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