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Src family tyrosine kinases (SFKs) [cytosol]
Stable Identifier
R-CFA-211064
Type
Set [DefinedSet]
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Hemostasis (Canis familiaris)
Cell surface interactions at the vascular wall (Canis familiaris)
PECAM1 interactions (Canis familiaris)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Costimulation by the CD28 family (Canis familiaris)
CD28 co-stimulation (Canis familiaris)
Phosphorylation of CD28 (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
CTLA4 inhibitory signaling (Canis familiaris)
Phosphorylation of CTLA-4 (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
SHP2 phosphatase binds CTLA-4 (Canis familiaris)
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
pCTLA-4:Src kinases:SHP2 [plasma membrane] (Canis familiaris)
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by SCF-KIT (Canis familiaris)
Dimerization of STATs (Canis familiaris)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Disassociation and translocation of STATs to the nucleus (Canis familiaris)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p-JAK2:SFKs:p-KIT complex:p-STAT dimers [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
GRB2 is indirectly recruited to p-KIT through SHP2 (Canis familiaris)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Indirect recruitment of GAB2 to p-KIT (Canis familiaris)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Indirect recruitment of PI3K to KIT via p(Y)-GAB2 (Canis familiaris)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
JAK2 binds to p-KIT (Canis familiaris)
JAK2:SFKS:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Phosphorylation and activation of VAV1 (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Phosphorylation of GAB2 by SFKs (Canis familiaris)
GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Phosphorylation of JAK2 (Canis familiaris)
JAK2:SFKS:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Phosphorylation of SHP2 by SFKs (Canis familiaris)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Phosphorylation of STATs (Canis familiaris)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p-JAK2:SFKs:p-KIT complex:p-STATs [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Phosphorylation of p-KIT on Y900 by Src kinases (Canis familiaris)
SFKs:p-8Y-KIT:sSCF dimer:p-8Y-KIT [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Recruitment of STATs (Canis familiaris)
p-JAK2:SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p-JAK2:SFKs:p-KIT complex:STATs [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Regulation of KIT signaling (Canis familiaris)
Interaction of APS and p-KIT (Canis familiaris)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Phosphorylation of APS (Canis familiaris)
APS dimer:p-c-Kit:SFKs complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
p-APS dimer:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Recruitment of CBL to KIT (Canis familiaris)
CBL:Grb2/p-APS:p-c-Kit complex [plasma membrane] (Canis familiaris)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Canis familiaris)
p-APS dimer:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Grb2:SOS:p-c-Kit/p-APS:p-c-Kit complex [plasma membrane] (Canis familiaris)
p-APS dimer:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
SHP2 interacts with p-KIT (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
SHP2:SFKs:p-KIT:sSCF dimer:p-KIT [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Synthesis of PIP3 from PIP2 by PI3K (Canis familiaris)
PI3K:p-KIT:sSCF dimer:p-KIT,PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
PI3K:p(Y)-GAB2:GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
GRB2:p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
p-SHP2:p-KIT complex [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
Src family tyrosine kinases (SFKs) [cytosol] (Canis familiaris)
Participants
members
FYN [cytosol]
(Canis familiaris)
LYN [cytosol]
(Canis familiaris)
YES1 [cytosol]
(Canis familiaris)
SRC [cytosol]
(Canis familiaris)
LCK [cytosol]
(Canis familiaris)
Participates
as a component of
SFKs:p-8Y-KIT:sSCF dimer:p-8Y-KIT [plasma membrane] (Canis familiaris)
SFKs:p-KIT complex [plasma membrane] (Canis familiaris)
p-Y201,Y218-CTLA-4 dimer:SFKs [plasma membrane] (Canis familiaris)
as an input of
Phosphorylation of CTLA-4 (Canis familiaris)
Inferred From
Src family tyrosine kinases (SFKs) [cytosol]
(Homo sapiens)
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