Reactome | spherical HDL [extracellular region]

spherical HDL [extracellular region]

Stable Identifier

R-CFA-265523

Type

Complex

Species

Canis familiaris

Compartment

extracellular region

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 4 APOA1 [extracellular region] (Canis familiaris)
x 160 CHEST [extracellular region]
x 40 CHOL [extracellular region]
x 140 PL [extracellular region]
x 20 TAGs [extracellular region]

Participates

as an output of

Nascent CMs transform into mature CMs (Canis familiaris)
nascent chylomicron + spherical HDL:apoC-II:apoC-III:apoE =>spherical HDL + chylomicron (Canis familiaris)

as an input of

HDLBP binds HDL (Canis familiaris)
TG-depleted chylomicron + spherical HDL => chylomicron remnant + spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III (Canis familiaris)
Spherical HDL binds membrane-associated free cholesterol and phospholipids (Canis familiaris)
Spherical HDL binds C and E apolipoproteins (Canis familiaris)
spherical HDL and SR-BI receptor form a complex at the cell surface (Canis familiaris)

as a component of

HDLBP:HDL [plasma membrane] (Canis familiaris)
spherical HDL:apoA-I:apoA-II:apoA-IV:apoC-II:apoC-III [extracellular region] (Canis familiaris)
spherical HDL:apoC-II:apoC-III:apoE [extracellular region] (Canis familiaris)

as a member of

Ligands of SCARB1 [extracellular region] (Canis familiaris)
Ligands of CD36 [extracellular region] (Canis familiaris)

as a candidate of

LDL,HDL [extracellular region] (Canis familiaris)

Inferred From

spherical HDL [extracellular region] (Homo sapiens)

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