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CASP8 [cytosol]
Stable Identifier
R-CFA-3465404
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
CASP8(1-374), Q38JA9
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Canis familiaris)
Apoptosis (Canis familiaris)
Caspase activation via extrinsic apoptotic signalling pathway (Canis familiaris)
Caspase activation via Death Receptors in the presence of ligand (Canis familiaris)
Regulation by c-FLIP (Canis familiaris)
Caspase-8 and FLIP(L) processing at DISC (Canis familiaris)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Canis familiaris)
CASP8 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Death Receptor Signaling (Canis familiaris)
TNF signaling (Canis familiaris)
Regulation of TNFR1 signaling (Canis familiaris)
Caspase-8 and FLIP(L) processing at TNFR signaling complex (Canis familiaris)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Canis familiaris)
CASP8 [cytosol] (Canis familiaris)
RIPK1 is cleaved by CASP8:FLIP(L) (Canis familiaris)
CASP8 [cytosol] (Canis familiaris)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Canis familiaris)
CASP8 [cytosol] (Canis familiaris)
TRADD:TRAF2:RIPK1(325-671):FADD:p43/p41CASP8:p43 FLIP(L) [cytosol] (Canis familiaris)
CASP8 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:Q38JA9
Gene Names
CASP8
Reference Genes
BioGPS Gene:488473 CASP8
ENSEMBL:ENSCAFG00845030024.1
KEGG:cfa:488473 CASP8
Monarch:488473 CASP8
NCBI Gene:488473 CASP8
UCSC:Q38JA9 CASP8
Reference Transcript
RefSeq:XM_005640425.1 CASP8
RefSeq:NM_001048029.1 CASP8
RefSeq:XM_005640423.1 CASP8
RefSeq:XM_038447314.1 CASP8
RefSeq:XM_005640424.2 CASP8
RefSeq:XM_038447313.1 CASP8
RefSeq:XM_005640427.1 CASP8
RefSeq:XM_038447312.1 CASP8
RefSeq:XM_005640426.2 CASP8
Other Identifiers
488473
Cfa.1722.1.S1_at
CfaAffx.18878.1.S1_s_at
GO:0001817
GO:0002682
GO:0004197
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006508
GO:0006915
GO:0006954
GO:0008233
GO:0008234
GO:0008625
GO:0009967
GO:0016787
GO:0030027
GO:0030154
GO:0030335
GO:0031264
GO:0031265
GO:0031625
GO:0032731
GO:0032991
GO:0034612
GO:0035877
GO:0036462
GO:0042802
GO:0042981
GO:0043009
GO:0043123
GO:0043124
GO:0045651
GO:0045862
GO:0048513
GO:0048856
GO:0051603
GO:0051604
GO:0060546
GO:0070269
GO:0071260
GO:0097110
GO:0097190
GO:0097191
GO:0097194
GO:0097342
GO:0140639
GO:1900119
Participates
as a component of
TRADD:TRAF2:RIPK1(325-671):FADD:p43/p41CASP8:p43 FLIP(L) [cytosol] (Canis familiaris)
DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Canis familiaris)
Other forms of this molecule
CASP8 [cytosol]
CASP8 [cytosol]
CASP8 [cytosol]
CASP8 [mitochondrial outer membrane]
CASP8 [mitochondrial outer membrane]
CASP8 [cytosol]
CASP8 [cytosol]
CASP8 [cytosol]
CASP8 [cytosol]
CASP8 [cytosol]
CASP8 [cytosol]
Inferred From
CASP8(1-374) [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_005640483.1
,
XP_005640484.1
,
NP_001041494.1
,
XP_038303240.1
,
XP_038303242.1
,
XP_005640480.1
,
XP_038303241.1
,
XP_005640481.1
,
XP_005640482.1
ENSEMBL
ENSCAFT00845053200
,
ENSCAFG00845030024
,
ENSCAFP00845041772
VGNC
38736
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