Reactome | DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane]

DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane]

Stable Identifier

R-CFA-3465431

Type

Complex

Species

Canis familiaris

Compartment

plasma membrane

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

CASP8 [cytosol] (Canis familiaris)
CASP9 [cytosol] (Canis familiaris)
TRADD:TRAF2:RIPK1:FADD [cytosol] (Canis familiaris)

Participates

as an input of

RIPK1 is cleaved by CASP8:FLIP(L) (Canis familiaris)

as an output of

Caspase-8 and FLIP(L) processing at TNFR signaling complex (Canis familiaris)
Caspase-8 and FLIP(L) processing at DISC (Canis familiaris)

Inferred From

TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Homo sapiens)

DISC:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Homo sapiens)

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