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Caspase-3 [cytosol]
Stable Identifier
R-CFA-350870
Type
Complex
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Other interleukin signaling (Canis familiaris)
Caspase-3 cleaves pro-interleukin-16 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Programmed Cell Death (Canis familiaris)
Apoptosis (Canis familiaris)
Apoptotic execution phase (Canis familiaris)
Apoptosis induced DNA fragmentation (Canis familiaris)
Translocation of caspase-3 to the nucleus (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Apoptotic cleavage of cellular proteins (Canis familiaris)
Apoptotic cleavage of cell adhesion proteins (Canis familiaris)
Caspase mediated cleavage of beta-catenin (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of Desmoglein 1 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of Desmoglein 2 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of Desmoglein 3 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of Desmoplakin (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of E-Cadherin (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of TJP1 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of Z0-2 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of occludin (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of plakophilin-1 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase 3-mediated cleavage of PKC delta (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase mediated cleavage of APC (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase mediated cleavage of C-IAP1 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of Acinus (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of Etk (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of MASK (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of MST3 (Canis familiaris)
Caspase-3, Caspase-7 [cytosol] (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of PKC theta (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of Rock-1 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of cytoskeletal proteins (Canis familiaris)
Caspase mediated cleavage of HIP-55 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase mediated cleavage of alpha-II-Fodrin (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of GAS2 (Canis familiaris)
Caspase-3, Caspase-7 [cytosol] (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of Tau (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of alpha adducin (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of gelsolin (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase-mediated cleavage of vimentin at DSVD (85) (Canis familiaris)
Caspase-3, Caspase-7 [cytosol] (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase activation via extrinsic apoptotic signalling pathway (Canis familiaris)
Caspase activation via Dependence Receptors in the absence of ligand (Canis familiaris)
Activation of caspase-3 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Caspase cleavage of DCC (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Intrinsic Pathway for Apoptosis (Canis familiaris)
Apoptotic factor-mediated response (Canis familiaris)
Cytochrome c-mediated apoptotic response (Canis familiaris)
Activation of caspases through apoptosome-mediated cleavage (Canis familiaris)
Cleavage of Procaspase-3 by the apoptosome (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
SMAC, XIAP-regulated apoptotic response (Canis familiaris)
XIAP binds CASP3 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
DIABLO:XIAP:Caspase-3 [cytosol] (Canis familiaris)
XIAP:Caspase-3 [cytosol] (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
XIAP:Caspase-3 [cytosol] (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Regulated Necrosis (Canis familiaris)
Pyroptosis (Canis familiaris)
CASP1 cleaves GSDMD (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
CASP3 cleaves GSDMD (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
CASP3 cleaves GSDME (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Death Receptor Signaling (Canis familiaris)
p75 NTR receptor-mediated signalling (Canis familiaris)
Cell death signalling via NRAGE, NRIF and NADE (Canis familiaris)
NADE modulates death signalling (Canis familiaris)
p75NTR:NADE promotes caspase2/3 activation (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Signaling by Hippo (Canis familiaris)
Cleavage of p-STK3 (p-MST2) by caspase 3 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
Cleavage of p-STK4 (p-MST1) by caspase 3 (Canis familiaris)
Caspase-3 [cytosol] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
CASP3(29-175):CASP3(176-277) [cytosol]
(Canis familiaris)
Participates
as an output of
p75NTR:NADE promotes caspase2/3 activation (Canis familiaris)
Cleavage of Procaspase-3 by the apoptosome (Canis familiaris)
Activation of caspase-3 (Canis familiaris)
as an input of
XIAP binds CASP3 (Canis familiaris)
Translocation of caspase-3 to the nucleus (Canis familiaris)
as a member of
Caspase-3, Caspase-7 [cytosol] (Canis familiaris)
as a component of
XIAP:Caspase-3 [cytosol] (Canis familiaris)
This entity regulates
Negatively
CASP1 cleaves GSDMD
(Canis familiaris)
Inferred From
Active Caspases 2, 3 [cytosol]
(Homo sapiens)
Caspase-3 [cytosol]
(Homo sapiens)
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