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NCOA2 [nucleoplasm]
Stable Identifier
R-CFA-376398
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
NCOA2, A0A8I3PYI4
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Cytoprotection by HMOX1 (Canis familiaris)
Fatty acid ligands activate PPARA (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
PPARA:RXRA Coactivator complex [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Endogenous sterols (Canis familiaris)
CYP7A1 7-hydroxylates CHOL (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
CYP7B1 7-hydroxylates 25OH-CHOL (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Recycling of bile acids and salts (Canis familiaris)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
Synthesis of bile acids and bile salts (Canis familiaris)
CYP7B1 7-hydroxylates 25OH-CHOL (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Canis familiaris)
27-hydroxycholesterol is 7alpha-hydroxylated (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Canis familiaris)
CYP7A1 7-hydroxylates CHOL (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
Regulation of lipid metabolism by PPARalpha (Canis familiaris)
Fatty acid ligands activate PPARA (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
PPARA:RXRA Coactivator complex [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Estrogen-dependent gene expression (Canis familiaris)
HATs and coactivators are recruited to the CTSD gene (Canis familiaris)
CTSD gene:ESR1:ESTG:SP1:USF1:USF2:NCOA:EP300:MED1 [nucleoplasm] (Canis familiaris)
NCOAs [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
NCOAs [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases activate PKNs (Canis familiaris)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Canis familiaris)
PKN1 stimulates association of AR with NCOA2 (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:NCOA2 [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3PYI4
Gene Names
NCOA2
Reference Genes
ENSEMBL:ENSCAFG00845025550.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845025550.1 NCOA2
Other Identifiers
486989
Cfa.3010.1.A1_s_at
CfaAffx.12590.1.S1_s_at
GO:0000122
GO:0000978
GO:0001162
GO:0003677
GO:0003682
GO:0003713
GO:0005102
GO:0005634
GO:0005654
GO:0005667
GO:0005737
GO:0005975
GO:0006351
GO:0006355
GO:0006629
GO:0007623
GO:0010468
GO:0010906
GO:0016604
GO:0016922
GO:0017162
GO:0019216
GO:0019904
GO:0030374
GO:0032570
GO:0032922
GO:0032991
GO:0043226
GO:0045475
GO:0045892
GO:0045944
GO:0046983
GO:0061629
GO:0140110
GO:1904017
Participates
as a candidate of
NCOAs [nucleoplasm] (Canis familiaris)
as an input of
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Canis familiaris)
PKN1 stimulates association of AR with NCOA2 (Canis familiaris)
as a component of
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
p-T774-PKN1:AR:Androgen:NCOA2 [nucleoplasm] (Canis familiaris)
as a member of
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
Other forms of this molecule
NCOA2 [nucleoplasm]
Inferred From
NCOA2 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000140396
Ensembl
ENSCAFG00845025550
,
ENSCAFT00845045687
,
ENSCAFP00845035851
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