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OFD1 [cytosol]
Stable Identifier
R-CFA-380318
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
OFD1, A0A8I3S6V4
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Prometaphase (Canis familiaris)
Recruitment of NuMA to mitotic centrosomes (Canis familiaris)
Association of NuMA with microtubules (Canis familiaris)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
p-T2055-NUMA1 homodimer:Mature centrosome:nucleated microtubules [cytosol] (Canis familiaris)
Mature centrosome:nucleated microtubules [cytosol] (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Translocation of NuMA to the centrosomes (Canis familiaris)
Mature centrosome enriched in gamma-TURC:p-T2055-NUMA1 homodimer [cytosol] (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Mitotic G2-G2/M phases (Canis familiaris)
G2/M Transition (Canis familiaris)
AURKA Activation by TPX2 (Canis familiaris)
TPX2 binds AURKA at centrosomes (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
TPX2 promotes AURKA autophosphorylation (Canis familiaris)
Centrosome:AURKA:TPX2:HMMR [cytosol] (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA:TPX2:HMMR [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Centrosome maturation (Canis familiaris)
Loss of proteins required for interphase microtubule organization from the centrosome (Canis familiaris)
Loss of C-Nap-1 from centrosomes (Canis familiaris)
cNAP-1 depleted centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Loss of Nlp from mitotic centrosomes (Canis familiaris)
Dissociation of Phospho-Nlp from the centrosome (Canis familiaris)
Nlp-depleted centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
centrosome containing phosphorylated Nlp [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Plk1-mediated phosphorylation of Nlp (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
centrosome containing phosphorylated Nlp [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Recruitment of mitotic centrosome proteins and complexes (Canis familiaris)
Recruitment of CDK11p58 to the centrosomes (Canis familiaris)
Centrosomes containing recruited CDK11p58 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Recruitment of Plk1 to centrosomes (Canis familiaris)
Centrosome associated Plk1 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Recruitment of additional gamma tubulin/ gamma TuRC to the centrosome (Canis familiaris)
Mature centrosomes enriched in gamma-TURC complexes [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Regulation of PLK1 Activity at G2/M Transition (Canis familiaris)
AJUBA binds centrosome-associated AURKA (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Centrosome:AURKA:AJUBA [cytosol] (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
AJUBA facilitates AURKA autophosphorylation (Canis familiaris)
Centrosome:AURKA:AJUBA [cytosol] (Canis familiaris)
Centrosome:AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
AURKA phosphorylates PLK1 (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
BORA binds PLK1 and AURKA (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA:p-S252-BORA:PLK1 [cytosol] (Canis familiaris)
Centrosome:p-T288-AURKA [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Organelle biogenesis and maintenance (Canis familiaris)
Cilium Assembly (Canis familiaris)
Anchoring of the basal body to the plasma membrane (Canis familiaris)
C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
C2CD3 binds the mother centriole (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
CEP164 recruits RAB3IP-carrying Golgi-derived vesicles to the basal body (Canis familiaris)
basal body:transition zone proteins [cytosol] (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Canis familiaris)
basal body:transition zone proteins [cytosol] (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
CP110 and CEP97 dissociate from the centriole (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
MARK4 binds ODF2 in the centriole (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
RAB3IP stimulates nucleotide exchange on RAB8A (Canis familiaris)
basal body:transition zone proteins:RAB3IP:RAB11A:GTP:Golgi-derived vesicle [cytosol] (Canis familiaris)
basal body:transition zone proteins [cytosol] (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Recruitment of transition zone proteins (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
basal body:transition zone proteins [cytosol] (Canis familiaris)
basal body [cytosol] (Canis familiaris)
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
The distal appendage proteins recruit TTBK2 (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Canis familiaris)
Centrosome:C2CD3:distal appendage proteins [cytosol] (Canis familiaris)
mother centriole:C2CD3 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Hedgehog (Canis familiaris)
Hedgehog 'off' state (Canis familiaris)
The intraflagellar transport A (IFT-A) complex is required for the transit of GLI:SUFU complexes to the ciliary base (Canis familiaris)
ciliary basal body regulators of Hh [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
The intraflagellar transport B (IFT-B) complex is required for the transit of GLI:SUFU complexes to the ciliary tip (Canis familiaris)
ciliary basal body regulators of Hh [cytosol] (Canis familiaris)
OFD1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3S6V4
Gene Names
OFD1
Reference Genes
ENSEMBL:ENSCAFG00845028661.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845028661.1 OFD1
Other Identifiers
480841
CfaAffx.18289.1.S1_at
CfaAffx.18295.1.S1_s_at
GO:0005515
Participates
as a component of
centrosome without CEP164, CCP110 or CEP97 [cytosol] (Canis familiaris)
mother centriole [cytosol] (Canis familiaris)
Nlp-depleted centrosome [cytosol] (Canis familiaris)
centrosome containing phosphorylated Nlp [cytosol] (Canis familiaris)
cNAP-1 depleted centrosome [cytosol] (Canis familiaris)
centrosome [cytosol] (Canis familiaris)
as a member of
ciliary basal body regulators of Hh [cytosol] (Canis familiaris)
Inferred From
OFD1 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000046651
Ensembl
ENSCAFG00845028661
,
ENSCAFT00845050859
,
ENSCAFP00845039869
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