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IGF1,2 [extracellular region]
Stable Identifier
R-CFA-381451
Type
Set [DefinedSet]
Species
Canis familiaris
Compartment
extracellular region
Synonyms
Insulin-like Growth Factor
Locations in the PathwayBrowser
Expand all
Hemostasis (Canis familiaris)
Platelet activation, signaling and aggregation (Canis familiaris)
Response to elevated platelet cytosolic Ca2+ (Canis familiaris)
Platelet degranulation (Canis familiaris)
Exocytosis of platelet alpha granule contents (Canis familiaris)
Platelet alpha granule contents [extracellular region] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (Canis familiaris)
IGFBP2 binds IGF forming IGF:IGFBP2 (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF:IGFBP2 [extracellular region] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGFBP4 binds IGF forming IGF:IGFBP4 (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF:IGFBP4 [extracellular region] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGFBP6 binds IGF forming IGF:IGFBP6 (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF:IGFBP6 [extracellular region] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
PAAP-A proteolyzes IGF:IGFBP4 (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF:IGFBP4 [extracellular region] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Canis familiaris)
IGF1,2 binds IGF1R (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:IGF1R autophosphorylates (Canis familiaris)
IGF1,2:IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1R signaling cascade (Canis familiaris)
IRS-related events triggered by IGF1R (Canis familiaris)
IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS1,4 (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:p-IGF1R:IRS1,4 [plasma membrane] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:p-Y1161,1165,1166-IGF1R binds IRS2 (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:p-IGF1R:IRS2 [plasma membrane] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Canis familiaris)
IGF1,2:p-IGF1R:IRS1,2,4 [plasma membrane] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:p-IGF1R:p-IRS1,2,4 [plasma membrane] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
SHC-related events triggered by IGF1R (Canis familiaris)
IGF1,2:p-Y1161,1165,1166-IGF1R binds SHC1 (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:p-3Y-IGF1R:SHC1 [plasma membrane] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1R phosphorylates SHC1 (Canis familiaris)
IGF1,2:p-3Y-IGF1R:SHC1 [plasma membrane] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:p-3Y-IGF1R:p-3Y-SHC1 [plasma membrane] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
p-3Y-SHC1 dissociates from IGF1R (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
IGF1,2:p-3Y-IGF1R:p-3Y-SHC1 [plasma membrane] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF1,2 [extracellular region] (Canis familiaris)
Participants
members
IGF1 [extracellular region]
(Canis familiaris)
IGF2 [extracellular region]
(Canis familiaris)
Participates
as an input of
IGF1,2 binds IGF1R (Canis familiaris)
IGFBP6 binds IGF forming IGF:IGFBP6 (Canis familiaris)
IGFBP2 binds IGF forming IGF:IGFBP2 (Canis familiaris)
IGFBP4 binds IGF forming IGF:IGFBP4 (Canis familiaris)
as a component of
IGF1,2:IGF1R [plasma membrane] (Canis familiaris)
IGF1,2:p-3Y-IGF1R [plasma membrane] (Canis familiaris)
IGF:IGFBP6 [extracellular region] (Canis familiaris)
IGF:IGFBP2 [extracellular region] (Canis familiaris)
IGF:IGFBP4 [extracellular region] (Canis familiaris)
as an output of
PAAP-A proteolyzes IGF:IGFBP4 (Canis familiaris)
as a member of
Platelet alpha granule contents [extracellular region] (Canis familiaris)
Inferred From
IGF1,2 [extracellular region]
(Homo sapiens)
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