Reactome | NTSR2 [plasma membrane]

NTSR2 [plasma membrane]

Stable Identifier

R-CFA-388918

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

NTSR2, A0A8I3PWE8

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR2 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR2 [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR2 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR2 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR2 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR2 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Neurotensin receptors can bind neurotensins (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2:NTS(151-163) [plasma membrane] (Canis familiaris)
        
        NTSR1,NTSR2 [plasma membrane] (Canis familiaris)
        
        NTSR2 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PWE8

Gene Names

NTSR2

Reference Genes

BioGPS Gene:482972 NTSR2

ENSEMBL:ENSCAFG00845028451.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845028451.1 NTSR2

KEGG Gene (Canis lupus familiaris):482972 NTSR2

Monarch:482972 NTSR2

NCBI Gene:482972 NTSR2

Reference Transcript

RefSeq:XM_540085.4 NTSR2

Other Identifiers

482972

CfaAffx.6313.1.S1_at

GO:0004930

GO:0007186

GO:0007200

GO:0016020

GO:0016492

GO:0023052

GO:0042391

GO:0060089

Participates

as a member of

NTSR1,NTSR2 [plasma membrane] (Canis familiaris)

Inferred From

NTSR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_540085.2

OpenTargets

ENSG00000169006

Ensembl

ENSCAFT00845050198, ENSCAFP00845039357, ENSCAFG00845028451