Reactome | TPM3 [cytosol]

TPM3 [cytosol]

Stable Identifier

R-CFA-390543

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

cytosol

Synonyms

TPM3, A0A8I3P0W2

Locations in the PathwayBrowser

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Muscle contraction (Canis familiaris)

- Smooth Muscle Contraction (Canis familiaris)
  - ATP Hydrolysis By Myosin (Canis familiaris)
    - ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
    - ATP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
  - Calcium Binds Caldesmon (Canis familiaris)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
    - Inactive Myosin Actin Contractile Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
  - Myosin Binds ATP (Canis familiaris)
    - ATP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
    - p-S CALD1-Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
  - Release Of ADP From Myosin (Canis familiaris)
    - ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
    - Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
      - Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
- Striated Muscle Contraction (Canis familiaris)
  - ATP Hydrolysis By Myosin (Canis familiaris)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
  - Calcium Binds Troponin-C (Canis familiaris)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
    - Inactive Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
  - Myosin Binds ATP (Canis familiaris)
    - ATP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
  - Release Of ADP From Myosin (Canis familiaris)
    - ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
    - Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
      - Thin Filament With Troponin Bound Calcium [cytosol] (Canis familiaris)
        
        Tropomyosin [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)

Signal Transduction (Canis familiaris)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
  - Signaling by Rho GTPases (Canis familiaris)
    - RHO GTPase cycle (Canis familiaris)
      - RHOV GTPase cycle (Canis familiaris)
        
        RHOV binds effectors at the plasma membrane (Canis familiaris)
        
        RHOV effectors [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)
        
        RHOV:GTP:RHOV effectors [plasma membrane] (Canis familiaris)
        
        RHOV effectors [cytosol] (Canis familiaris)
        
        TPM3 [cytosol] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3P0W2

Gene Names

TPM3

Reference Genes

ENSEMBL:ENSCAFG00845015257.1

UCSC:A0A8I3P0W2 TPM3

Other Identifiers

480137

Cfa.12778.1.A1_at

Cfa.12789.1.A1_at

CfaAffx.26506.1.S1_s_at

CfaAffx.26510.1.S1_at

CfaAffx.26511.1.S1_at

GO:0001725

GO:0003012

GO:0003779

GO:0005829

GO:0005856

GO:0005884

GO:0006936

GO:0007015

GO:0008092

GO:0015629

GO:0051015

Participates

as a candidate of

RHOV effectors [cytosol] (Canis familiaris)

as a member of

Tropomyosin [cytosol] (Canis familiaris)

Inferred From

TPM3 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSCAFT00845027340, ENSCAFP00845021519, ENSCAFG00845015257