Reactome | CHRM1 [plasma membrane]

CHRM1 [plasma membrane]

Stable Identifier

R-CFA-390628

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

CHRM1, A0A8I3RVA9

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Amine ligand-binding receptors (Canis familiaris)
        
        Muscarinic acetylcholine receptors (Canis familiaris)
        
        CHRM1,3,5 bind CHRM1,3,5 antagonists (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:CHRM1,3,5 antagonists [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 bind acetylcholine (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM1 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3RVA9

Gene Names

CHRM1

Reference Genes

BioGPS Gene:483776 CHRM1

ENSEMBL:ENSCAFG00845007309.1

KEGG:cfa:483776 CHRM1

Monarch:483776 CHRM1

NCBI Gene:483776 CHRM1

UCSC:A0A8I3RVA9 CHRM1

Reference Transcript

Other Identifiers

483776

CfaAffx.23751.1.S1_at

GO:0004930

GO:0004993

GO:0005886

GO:0007186

GO:0007187

GO:0007197

GO:0007268

GO:0016907

GO:0022600

GO:0023052

GO:0030054

GO:0030425

GO:0040012

GO:0043270

GO:0045202

GO:0045211

GO:0046541

GO:0050877

GO:0050890

GO:0060078

GO:0060089

GO:0098664

GO:0098685

GO:0098981

GO:0099170

Participates

as a member of

CHRM1,3,5 [plasma membrane] (Canis familiaris)

Inferred From

CHRM1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_540897.2, XP_005631654.1

ENSEMBL

ENSCAFP00845010054, ENSCAFT00845012926, ENSCAFP00845010076, ENSCAFT00845012901