Reactome | CHRM5 [plasma membrane]

CHRM5 [plasma membrane]

Stable Identifier

R-CFA-390678

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

plasma membrane

Synonyms

CHRM5, A0A8I3PH67

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        GPCRs that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Amine ligand-binding receptors (Canis familiaris)
        
        Muscarinic acetylcholine receptors (Canis familiaris)
        
        CHRM1,3,5 bind CHRM1,3,5 antagonists (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:CHRM1,3,5 antagonists [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 bind acetylcholine (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5:AcCho [plasma membrane] (Canis familiaris)
        
        CHRM1,3,5 [plasma membrane] (Canis familiaris)
        
        CHRM5 [plasma membrane] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PH67

Gene Names

CHRM5

Reference Genes

ENSEMBL:ENSCAFG00845020291.1

UCSC:A0A8I3PH67 CHRM5

Other Identifiers

CfaAffx.229.1.S1_at

GO:0001696

GO:0004930

GO:0005886

GO:0007186

GO:0007213

GO:0015872

GO:0016907

GO:0019226

GO:0022600

GO:0030054

GO:0045202

GO:0045211

GO:0050877

GO:0060089

Participates

as a member of

CHRM1,3,5 [plasma membrane] (Canis familiaris)

Inferred From

CHRM5 [plasma membrane] (Homo sapiens)

Cross References

ENSEMBL

ENSCAFT00845035731, ENSCAFP00845027955