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Me2K10-HIST2H3A [nucleoplasm]
Stable Identifier
R-CFA-427407
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
J9P7X1
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular Senescence (Canis familiaris)
Senescence-Associated Secretory Phenotype (SASP) (Canis familiaris)
EHMT1:EHMT2 methylates IL6 promoter (Canis familiaris)
IL6 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
EHMT1:EHMT2 methylates IL8 promoter (Canis familiaris)
IL8 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
Chromatin organization (Canis familiaris)
Chromatin modifying enzymes (Canis familiaris)
HDMs demethylate histones (Canis familiaris)
KDM3A, KDM3B, KDM7A, PHF2:ARID5B, PHF8 demethylate Me2K10-histone H3 (Canis familiaris)
Me2K10-histone H3 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
KDM4A, KDM4B, KDM4C, KDM4D demethylate Me2K10-histone H3 (Canis familiaris)
Me2K10-histone H3 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
KDM4A, KDM4B, KDM4C, KDM4D, MINA demethylate Me3K10-histone H3 (Canis familiaris)
Me2K10-histone H3 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
PKMTs methylate histone lysines (Canis familiaris)
EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Canis familiaris)
Me2K10-histone H3 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Canis familiaris)
Me2K10-histone H3 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
Gene expression (Transcription) (Canis familiaris)
Epigenetic regulation of gene expression (Canis familiaris)
Negative epigenetic regulation of rRNA expression (Canis familiaris)
SIRT1 negatively regulates rRNA expression (Canis familiaris)
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
eNoSC [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
eNoSC deacetylates histone H3 (Canis familiaris)
eNoSC [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
eNoSC dimethylates histone H3 at lysine-9 (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
eNoSC [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
RNA Polymerase I Transcription (Canis familiaris)
RNA Polymerase I Promoter Clearance (Canis familiaris)
RNA Polymerase I Promoter Escape (Canis familiaris)
Elongation of pre-rRNA transcript (Canis familiaris)
Chromatin (H3K9me2):CBX3 [nucleoplasm] (Canis familiaris)
Chromatin (H3K9me2) [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
RNA Polymerase I Promoter Opening (Canis familiaris)
UBF-1 Binds rDNA Promoter (Canis familiaris)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Canis familiaris)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
Hemostasis (Canis familiaris)
Factors involved in megakaryocyte development and platelet production (Canis familiaris)
JMJD1C demethylates H3K9 mono- and di-methylation (Canis familiaris)
Histone H3 mono or di-methylated at K9 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Estrogen-dependent gene expression (Canis familiaris)
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Canis familiaris)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Canis familiaris)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
KDM1A is recruited to MYC and BCL2 genes (Canis familiaris)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Canis familiaris)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Canis familiaris)
MYC gene, BCL2 gene: H3K9me2 nucleosome [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Canis familiaris)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Canis familiaris)
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Me2K10-HIST2H3A [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:J9P7X1
Reference Genes
ENSEMBL:ENSCAFG00000024443
Participates
as a candidate of
Me2K10-histone H3 [nucleoplasm] (Canis familiaris)
as a member of
Histone H3 dimethylated at lysine-9 [nucleoplasm] (Canis familiaris)
Other forms of this molecule
2xAcK-HIST2H3A [nucleoplasm]
Me2aR27-HIST2H3A [nucleoplasm]
Me2aR18-HIST2H3A [nucleoplasm]
Me2sR9-HIST2H3A [nucleoplasm]
Me2sR3-HIST2H3A [nucleoplasm]
phospho-AcK9,14-p-S10-HIST2H3A [nucleoplasm]
phospho-AcK14,18,79-p-S10-HIST2H3A [nucleoplasm]
phospho-AcK9,14,18-p-S10,T11-HIST2H3A [nucleoplasm]
phospho-AcK14,18-p-S10,T11-HIST2H3A [nucleoplasm]
phospho-AcK9,14,18,79-p-S10,T11-HIST2H3A [nucleoplasm]
phospho-AcK14,18-p-S10-HIST2H3A [nucleoplasm]
phospho-AcK14,18,79-p-T11-HIST2H3A [nucleoplasm]
phospho-AcK14,18-p-T11-HIST2H3A [nucleoplasm]
phospho-AcK14,18,79-p-S10,T11-HIST2H3A [nucleoplasm]
Me2K28-HIST2H3A [nucleoplasm]
MeK37-HIST2H3A [nucleoplasm]
MeK80-HIST2H3A [nucleoplasm]
Me3K80-HIST2H3A [nucleoplasm]
Me2K80-HIST2H3A [nucleoplasm]
Me3K37-HIST2H3A [nucleoplasm]
Me2K37-HIST2H3A [nucleoplasm]
MeK-HIST2H3A [nucleoplasm]
MeK28-HIST2H3A [nucleoplasm]
MeK10-HIST2H3A [cytosol]
HIST2H3A [cytosol]
Me2K5-HIST2H3A [nucleoplasm]
HIST2H3A [nucleoplasm]
Me3K28-HIST2H3A [nucleoplasm]
Me3K5-HIST2H3A [nucleoplasm]
Me2K5,Me2aR3-HIST2H3A [nucleoplasm]
Ack10-HIST2H3A [nucleoplasm]
Me3K10-HIST2H3A [nucleoplasm]
phospho-p-T12, Me3K-10-HIST2H3A [nucleoplasm]
phospho-p-T12, Me2K-10-HIST2H3A [nucleoplasm]
phospho-p-T12,MeK-HIST2H3A [nucleoplasm]
phospho-p-T12-HIST2H3A [nucleoplasm]
AcK5-HIST2H3A [nucleoplasm]
AcK19-HIST2H3A [nucleoplasm]
Ack15-HIST2H3A [nucleoplasm]
AcK24-HIST2H3A [nucleoplasm]
MeR9-HIST2H3A [nucleoplasm]
MeR27-HIST2H3A [nucleoplasm]
MeR3-HIST2H3A [nucleoplasm]
MeR18-HIST2H3A [nucleoplasm]
Cit18-HIST2H3A [nucleoplasm]
Cit9-HIST2H3A [nucleoplasm]
Cit27-HIST2H3A [nucleoplasm]
MeK5-HIST2H3A [nucleoplasm]
Me2aR3-HIST2H3A [nucleoplasm]
Inferred From
Me2K10-HIST2H3A [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
N6,N6-dimethyl-L-lysine at 10 (in Homo sapiens)
Coordinate
10
PsiMod Name
N6,N6-dimethyl-L-lysine [MOD:00084]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.
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