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PAK3 [cytosol]
Stable Identifier
R-CFA-428457
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
A0A8I3PNN9
Locations in the PathwayBrowser
Expand all
Developmental Biology (Canis familiaris)
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
EPH-Ephrin signaling (Canis familiaris)
Ephrin signaling (Canis familiaris)
PAK binds RAC and bPIX (Canis familiaris)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Canis familiaris)
PAK1/3, 2 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK1/3, 2 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAKs autophosphorylate (Canis familiaris)
EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:PAK1,3 [plasma membrane] (Canis familiaris)
PAK1/3, 2 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK1/3, 2 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Semaphorin interactions (Canis familiaris)
Sema3A PAK dependent Axon repulsion (Canis familiaris)
Activation of PAK by Rac1 (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Autophosphorylation of PAK (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAK [plasma membrane] (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Costimulation by the CD28 family (Canis familiaris)
CD28 co-stimulation (Canis familiaris)
CD28 dependent Vav1 pathway (Canis familiaris)
Activation of PAKs by RAC1 and CDC42 (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
TCR signaling (Canis familiaris)
Generation of second messenger molecules (Canis familiaris)
NCK binds PAK (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
p-SLP-76:NCK:PAK [cytosol] (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
C-type lectin receptors (CLRs) (Canis familiaris)
CD209 (DC-SIGN) signaling (Canis familiaris)
PAK phosphorylates p21 RAF1 on S338 (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK6/MAPK4 signaling (Canis familiaris)
Activation of PAKs by RAC1 and CDC42 (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK1,2,3:CDC42:GTP, RAC1:GTP [plasma membrane] (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Autophosphorylation of PAK1,2,3 (Canis familiaris)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Canis familiaris)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
VEGFR2 mediated vascular permeability (Canis familiaris)
PAK1-3 autophosphorylates (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK1-3 dimer disassociates (Canis familiaris)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
RAC1 binds PAK1-3 (Canis familiaris)
2 x p-VAV family:PIP3:RAC1:GTP:PAK 1-3 [plasma membrane] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK1,2,3 dimer [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases activate PAKs (Canis familiaris)
Autophosphorylation of PAK1,2,3 (Canis familiaris)
CDC42:GTP,RAC1:GTP:PAK1,PAK2,PAK3 [plasma membrane] (Canis familiaris)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
RAC1 and CDC42 activate PAK3 (Canis familiaris)
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
RHO GTPase cycle (Canis familiaris)
CDC42 GTPase cycle (Canis familiaris)
CDC42 binds effectors at the plasma membrane (Canis familiaris)
CDC42 effectors [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
CDC42:GTP:CDC42 effectors [plasma membrane] (Canis familiaris)
CDC42 effectors [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
RAC1 GTPase cycle (Canis familiaris)
RAC1 binds effectors at the plasma membrane (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
RAC1:GTP:RAC1 effectors [plasma membrane] (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
RHOU GTPase cycle (Canis familiaris)
RHOU binds effectors at the plasma membrane (Canis familiaris)
RHOU effectors [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
RHOU:GTP:RHOU effectors [plasma membrane] (Canis familiaris)
RHOU effectors [cytosol] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
PAK3 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3PNN9
Reference Genes
ENSEMBL:ENSCAFG00845022264.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845022264.1
Other Identifiers
CfaAffx.27802.1.S1_s_at
CfaAffx.27807.1.S1_at
GO:0000165
GO:0003824
GO:0004672
GO:0004708
GO:0005524
GO:0006468
GO:0007010
GO:0007409
GO:0014069
GO:0016020
GO:0016358
GO:0016740
GO:0023052
GO:0030154
GO:0030833
GO:0031267
GO:0034330
GO:0036211
GO:0043226
GO:0048856
GO:0060996
GO:0060997
GO:0065003
GO:0071407
GO:0098978
GO:0099175
GO:0140096
Participates
as a member of
PAK1/3, 2 [cytosol] (Canis familiaris)
PAK1,2,3 [cytosol] (Canis familiaris)
as an output of
RAC1 and CDC42 activate PAK3 (Canis familiaris)
as a component of
CDC42:GTP,RAC1:GTP:PAK3 [plasma membrane] (Canis familiaris)
PAK3 dimer [cytosol] (Canis familiaris)
Other forms of this molecule
phospho-p-S154,T436-PAK3 [plasma membrane]
phospho-p-S154,T436-PAK3 [cytosol]
Inferred From
PAK3 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSCAFT00845039290
,
ENSCAFG00845022264
,
ENSCAFP00845030777
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