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NCOA1 [nucleoplasm]
Stable Identifier
R-CFA-442496
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
NCOA1, A0A8I3PRC4
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Cytoprotection by HMOX1 (Canis familiaris)
Fatty acid ligands activate PPARA (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
PPARA:RXRA Coactivator complex [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Endogenous sterols (Canis familiaris)
CYP7A1 7-hydroxylates CHOL (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
CYP7B1 7-hydroxylates 25OH-CHOL (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Recycling of bile acids and salts (Canis familiaris)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
Synthesis of bile acids and bile salts (Canis familiaris)
CYP7B1 7-hydroxylates 25OH-CHOL (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Canis familiaris)
27-hydroxycholesterol is 7alpha-hydroxylated (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Canis familiaris)
CYP7A1 7-hydroxylates CHOL (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
Regulation of lipid metabolism by PPARalpha (Canis familiaris)
Fatty acid ligands activate PPARA (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
PPARA:RXRA Coactivator complex [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Estrogen-dependent gene expression (Canis familiaris)
HATs and coactivators are recruited to the CTSD gene (Canis familiaris)
CTSD gene:ESR1:ESTG:SP1:USF1:USF2:NCOA:EP300:MED1 [nucleoplasm] (Canis familiaris)
NCOAs [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NCOAs [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
Histone acetyltransferases are recruited to the TFF1 gene (Canis familiaris)
ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs [nucleoplasm] (Canis familiaris)
histone acetyltransferases [nucleoplasm] (Canis familiaris)
NCOA1,NCOA3 [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
histone acetyltransferases [nucleoplasm] (Canis familiaris)
NCOA1,NCOA3 [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1 binds ESR1:estrogen:TGFA gene (Canis familiaris)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1 recruits EP300 to TGFA promoter (Canis familiaris)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
ESR1:estrogen:TFGA gene:NCOA1:EP300 [nucleoplasm] (Canis familiaris)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NR1H2 and NR1H3-mediated signaling (Canis familiaris)
NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis (Canis familiaris)
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux (Canis familiaris)
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1 recruits EP300 to the ABCA1 promoter (Canis familiaris)
EP300:NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Canis familiaris)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Canis familiaris)
NCOA1 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3PRC4
Gene Names
NCOA1
Reference Genes
ENSEMBL:ENSCAFG00845024663.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845024663.1 NCOA1
Other Identifiers
475684
Cfa.15162.1.S1_at
Cfa.9842.1.A1_at
Cfa.9842.1.A1_s_at
CfaAffx.7029.1.S1_s_at
GO:0000435
GO:0000785
GO:0002155
GO:0003677
GO:0003682
GO:0003713
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0012501
GO:0016071
GO:0016922
GO:0023052
GO:0030154
GO:0030331
GO:0030374
GO:0032991
GO:0042789
GO:0043065
GO:0043226
GO:0045666
GO:0045893
GO:0045944
GO:0046983
GO:0048856
GO:0060713
GO:0090575
GO:0140110
GO:1904017
Participates
as an input of
NCOA1 binds the UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand complex (Canis familiaris)
NCOA1 binds the ABCA1gene:NR1H2,3:RXR:NR1H2,3 ligands complex (Canis familiaris)
NCOA1 binds ESR1:estrogen:TGFA gene (Canis familiaris)
NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Canis familiaris)
as a component of
UGT1A3 gene:NR1H2,3:RXR:NR1H2,3 ligand:NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1:NR1H2,3:RXR:NR1H2,3 ligand:ABCA1 gene [nucleoplasm] (Canis familiaris)
ESR1 dimer:estrogen:TFGA gene:NCOA1 [nucleoplasm] (Canis familiaris)
NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
as a member of
NCOA1,NCOA3 [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
as a candidate of
NCOAs [nucleoplasm] (Canis familiaris)
Other forms of this molecule
NCOA1 [nucleoplasm]
Inferred From
NCOA1 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000084676
Ensembl
ENSCAFG00845024663
,
ENSCAFT00845043605
,
ENSCAFP00845034161
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