Reactome | CCL23 [extracellular region]

CCL23 [extracellular region]

Stable Identifier

R-CFA-444564

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

extracellular region

Synonyms

CCL23-2, A0A8I3N5K9

Locations in the PathwayBrowser

Expand all

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR downstream signalling (Canis familiaris)
    - G alpha (i) signalling events (Canis familiaris)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
      - The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
    - G alpha (q) signalling events (Canis familiaris)
      - Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
      - The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
        
        Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Formyl peptide receptors bind formyl peptides and many other ligands (Canis familiaris)
        
        FPR2 binds FPR2 ligands (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)
        
        FPR2:FPR2 ligands [plasma membrane] (Canis familiaris)
        
        FPR2 ligands [extracellular region] (Canis familiaris)
        
        CCL23 [extracellular region] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N5K9

Gene Names

CCL23

Reference Genes

BioGPS Gene:480602 CCL23

ENSEMBL:ENSCAFG00845009019.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845009019.1 CCL23

Monarch:480602 CCL23

NCBI Gene:480602 CCL23

Reference Transcript

RefSeq:XM_537722.5 CCL23

Other Identifiers

480602

Cfa.12237.1.A1_at

GO:0002376

GO:0005576

GO:0006955

GO:0008009

GO:0048018

GO:0048870

GO:0098772

Participates

as a member of

FPR2 ligands [extracellular region] (Canis familiaris)

Inferred From

CCL23-2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

XP_537722.1

OpenTargets

ENSG00000274736

Ensembl

ENSCAFT00845015886, ENSCAFG00845009019, ENSCAFP00845012362

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