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phospho-MAP3K7 [endosome membrane]
Stable Identifier
R-CFA-450332
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
endosome membrane
Synonyms
p-T184,T187-MAP3K7, A0A8I3N7L6
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Innate Immune System (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Canis familiaris)
phospho-MAP3K7 [endosome membrane] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Canis familiaris)
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Canis familiaris)
phospho-MAP3K7 [endosome membrane] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3N7L6
Gene Names
MAP3K7
Reference Genes
BioGPS Gene:102156745 MAP3K7
ENSEMBL:ENSCAFG00845008051.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845008051.1 MAP3K7
KEGG Gene (Canis lupus familiaris):102156745 MAP3K7
Monarch:102156745 MAP3K7
NCBI Gene:102156745 MAP3K7
Reference Transcript
RefSeq:XM_005627639.2 MAP3K7
Other Identifiers
102156745
CfaAffx.5642.1.S1_s_at
GO:0000165
GO:0000287
GO:0002376
GO:0002726
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0004709
GO:0005524
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0006954
GO:0007165
GO:0007249
GO:0007254
GO:0016740
GO:0023052
GO:0030971
GO:0032743
GO:0034142
GO:0036211
GO:0038066
GO:0038172
GO:0038173
GO:0042742
GO:0042802
GO:0043123
GO:0043226
GO:0051403
GO:0070498
GO:0097110
GO:0098542
GO:0140096
GO:0140672
GO:1901224
GO:1990450
Participates
as a component of
p-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex [endosome membrane] (Canis familiaris)
Other forms of this molecule
MAP3K7 [cytosol]
MAP3K7 [cytosol]
phospho-MAP3K7 [cytosol]
phospho-MAP3K7 [cytosol]
phospho-MAP3K7 [cytosol]
MAP3K7 [endosome membrane]
MAP3K7 [cytosol]
phospho-MAP3K7 [cytosol]
Inferred From
p-T184,T187-MAP3K7 [endosome membrane]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 184 (in Homo sapiens)
Coordinate
184
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 187 (in Homo sapiens)
Coordinate
187
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
XP_005627696.1
OpenTargets
ENSG00000135341
Ensembl
ENSCAFG00845008051
,
ENSCAFP00845011040
,
ENSCAFT00845014240
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