Reactome | NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm]

NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm]

Stable Identifier

R-CFA-5340274

Type

Complex

Species

Canis familiaris

Compartment

nucleoplasm

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

NCOA1 [nucleoplasm] (Canis familiaris)
NCOA2 [nucleoplasm] (Canis familiaris)
NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Canis familiaris)
RXRA [nucleoplasm] (Canis familiaris)

Participates

as an output of

NR1H4:DCA,CDCA,LCHA binds RXRA and NCOA1,2 (Canis familiaris)

This entity regulates

Negatively

27-hydroxycholesterol is 7alpha-hydroxylated (Canis familiaris)
CYP7A1 7-hydroxylates CHOL (Canis familiaris)
CYP7B1 7-hydroxylates 25OH-CHOL (Canis familiaris)

Positively

SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Canis familiaris)

Inferred From

NCOA1,2:RXRA:NR1H4:DCA,CDCA,LCHA [nucleoplasm] (Homo sapiens)

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