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IQGAP1 [cytosol]
Stable Identifier
R-CFA-5626371
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
F1PJ65
Locations in the PathwayBrowser
Expand all
Signal Transduction (Canis familiaris)
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF/MAP kinase cascade (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
Dissociation of RAS:RAF complex (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
Dual mechanism MAPK inhibitors bind MAPKs (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
MAP2Ks and MAPKs bind to the activated RAF complex (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RAF phosphorylates MAP2K dimer (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Canis familiaris)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Canis familiaris)
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases activate IQGAPs (Canis familiaris)
GTP-bound RAC1 and CDC42 bind IQGAPs (Canis familiaris)
IQGAP [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Canis familiaris)
IQGAP [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
IQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1 (Canis familiaris)
CDH1 dimer:CTTNB1:CTTNA1:IQGAP1:MEN1 [plasma membrane] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Canis familiaris)
IQGAP [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
IQGAPs bind CALM1 (Canis familiaris)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Canis familiaris)
IQGAP [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Canis familiaris)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Canis familiaris)
IQGAP [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
IQGAPs bind F-actin, which is inhibited by calmodulin (Canis familiaris)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Canis familiaris)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Canis familiaris)
IQGAP [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Canis familiaris)
IQGAP [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RAC1:GTP,CDC42:GTP:IQGAPs:CALM1:4Ca2+ [plasma membrane] (Canis familiaris)
RAC1,CDC42:GTP:IQGAPs [plasma membrane] (Canis familiaris)
IQGAP [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RHO GTPase cycle (Canis familiaris)
RAC1 GTPase cycle (Canis familiaris)
RAC1 binds effectors at the plasma membrane (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RAC1:GTP:RAC1 effectors [plasma membrane] (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RAC2 GTPase cycle (Canis familiaris)
RAC2 binds effectors at the plasma membrane (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RAC2:GTP:RAC2 cytosolic effectors [plasma membrane] (Canis familiaris)
RAC2 plasma membrane effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RHOA GTPase cycle (Canis familiaris)
RHOA binds effectors at the plasma membrane (Canis familiaris)
RHOA plasma membrane effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RHOA:GTP:cytosolic RHOA effectors [plasma membrane] (Canis familiaris)
RHOA plasma membrane effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RHOC GTPase cycle (Canis familiaris)
RHOC binds effectors at the plasma membrane (Canis familiaris)
RHOC effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RHOC:GTP:RHOC effectors [plasma membrane] (Canis familiaris)
RHOC effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RHOU GTPase cycle (Canis familiaris)
RHOU binds effectors at the plasma membrane (Canis familiaris)
RHOU effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RHOU:GTP:RHOU effectors [plasma membrane] (Canis familiaris)
RHOU effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RHOV GTPase cycle (Canis familiaris)
RHOV binds effectors at the plasma membrane (Canis familiaris)
RHOV effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
RHOV:GTP:RHOV effectors [plasma membrane] (Canis familiaris)
RHOV effectors [cytosol] (Canis familiaris)
IQGAP1 dimer [cytosol] (Canis familiaris)
IQGAP1 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:F1PJ65
Reference Genes
ENSEMBL:ENSCAFG00000012639
Participates
as a component of
IQGAP1 dimer [cytosol] (Canis familiaris)
as a candidate of
RAF/MAPK scaffolds [cytosol] (Canis familiaris)
Other forms of this molecule
IQGAP1 [plasma membrane]
IQGAP1 [secretory granule membrane]
Inferred From
IQGAP1 [cytosol]
(Homo sapiens)
Cross References
VGNC
42081
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