Reactome | RAC1:GDP [plasma membrane]

RAC1:GDP [plasma membrane]

Stable Identifier

R-CFA-5674631

Type

Complex

Species

Canis familiaris

Compartment

plasma membrane

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

GDP [cytosol]
Homologues of RAC1 [plasma membrane] (Canis familiaris)

Participates

as an input of

RAC1 GDIs block activation of RAC1 (Canis familiaris)
RAC1 GEFs activate RAC1 (Canis familiaris)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Canis familiaris)
DOCK7 activates RAC1 (Canis familiaris)
DOCK3 activates RAC1 (Canis familiaris)
Activation of RAC1 by VAV (Canis familiaris)
Activation of RAC1 by CRKII:DOCK180:ELMO (Canis familiaris)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Canis familiaris)
p-VAV family:PIP3 binds RAC1:GDP (Canis familiaris)
Activation of RAC1 by the PXN:CRK complex (Canis familiaris)

as an output of

RAC1 GAPs stimulate RAC1 GTPase activity (Canis familiaris)
p-VAV1,2,3 exchange 6TGTP for GDP on RAC1 (Canis familiaris)

as a component of

p-VAV family:PIP3:RAC1:GDP [plasma membrane] (Canis familiaris)

Inferred From

RAC1:6TGTP [plasma membrane] (Homo sapiens)

RAC1:GDP [plasma membrane] (Homo sapiens)

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