Reactome | TIMELESS [nucleoplasm]

TIMELESS [nucleoplasm]

Stable Identifier

R-CFA-5684982

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

TIMELESS, A0A8I3N475

Locations in the PathwayBrowser

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DNA Repair (Canis familiaris)

- DNA Double-Strand Break Repair (Canis familiaris)
  - Homology Directed Repair (Canis familiaris)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Canis familiaris)
      - Processing of DNA double-strand break ends (Canis familiaris)
        
        Activation of CHEK1 at resected DNA DSBs (Canis familiaris)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Canis familiaris)
        
        TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)
        
        TIMELESS [nucleoplasm] (Canis familiaris)
        
        TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)
        
        TIMELESS [nucleoplasm] (Canis familiaris)
        
        CHEK1 is recruited to resected DNA DSBs (Canis familiaris)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Canis familiaris)
        
        TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)
        
        TIMELESS [nucleoplasm] (Canis familiaris)
        
        TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)
        
        TIMELESS [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3N475

Gene Names

TIMELESS

Reference Genes

BioGPS Gene:481112 TIMELESS

ENSEMBL:ENSCAFG00845008229.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845008229.1 TIMELESS

KEGG Gene (Canis lupus familiaris):481112 TIMELESS

Monarch:481112 TIMELESS

NCBI Gene:481112 TIMELESS

Reference Transcript

RefSeq:XM_005625506.1 TIMELESS

Other Identifiers

481112

CfaAffx.1163.1.S1_s_at

CfaAffx.1164.1.S1_at

Participates

as a component of

TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)

Inferred From

TIMELESS [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_005625563.1

OpenTargets

ENSG00000111602

Ensembl

ENSCAFG00845008229, ENSCAFT00845014502, ENSCAFP00845011237

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