Reactome | TIPIN [nucleoplasm]

TIPIN [nucleoplasm]

Stable Identifier

R-CFA-5684983

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

TIPIN, A0A8I3S1C7

Locations in the PathwayBrowser

Expand all

DNA Repair (Canis familiaris)

- DNA Double-Strand Break Repair (Canis familiaris)
  - Homology Directed Repair (Canis familiaris)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Canis familiaris)
      - Processing of DNA double-strand break ends (Canis familiaris)
        
        Activation of CHEK1 at resected DNA DSBs (Canis familiaris)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Canis familiaris)
        
        TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)
        
        TIPIN [nucleoplasm] (Canis familiaris)
        
        TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)
        
        TIPIN [nucleoplasm] (Canis familiaris)
        
        CHEK1 is recruited to resected DNA DSBs (Canis familiaris)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Canis familiaris)
        
        TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)
        
        TIPIN [nucleoplasm] (Canis familiaris)
        
        TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)
        
        TIPIN [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3S1C7

Gene Names

TIPIN

Reference Genes

BioGPS Gene:100683743 TIPIN

ENSEMBL:ENSCAFG00845015229.1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845015229.1 TIPIN

KEGG Gene (Canis lupus familiaris):100683743 TIPIN

Monarch:100683743 TIPIN

NCBI Gene:100683743 TIPIN

Reference Transcript

Other Identifiers

100683743

CfaAffx.26442.1.S1_at

GO:0000076

GO:0000077

GO:0000278

GO:0000785

GO:0005634

GO:0005694

GO:0005737

GO:0006260

GO:0006974

GO:0007049

GO:0008284

GO:0009411

GO:0023052

GO:0031297

GO:0031573

GO:0043226

GO:0044770

Participates

as a component of

TIMELESS:TIPIN [nucleoplasm] (Canis familiaris)

Inferred From

TIPIN [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_013965141.1, XP_013965142.1, XP_003433975.3

OpenTargets

ENSG00000075131

Ensembl

ENSCAFT00845027182, ENSCAFG00845015229, ENSCAFP00845021385

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