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GTF2A2 [nucleoplasm]
Stable Identifier
R-CFA-65533
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
GTF2A2, A0A8I3P2N9
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
RNA Polymerase II Pre-transcription Events (Canis familiaris)
Abortive Initiation Before Second Transition (Canis familiaris)
Pol II Promoter Escape Complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Abortive initiation after formation of the first phosphodiester bond (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II transcription complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Fall Back to Closed Pre-initiation Complex (Canis familiaris)
pol II closed pre-initiation complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II open pre-initiation complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA Polymerase II Transcription Initiation And Promoter Clearance (Canis familiaris)
RNA Polymerase II Promoter Escape (Canis familiaris)
Addition of Nucleotides 5 through 9 on the growing Transcript (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Addition of the fourth nucleotide on the Nascent Transcript: Second Transition (Canis familiaris)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II transcription complex containing 4 nucleotide long transcript [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Addition of the third nucleotide on the nascent transcript (Canis familiaris)
pol II transcription complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Unwinding DNA for the nascent transcript (Canis familiaris)
pol II transcription complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Unwinding of DNA for the Nascent Transcript: Second Transition (Canis familiaris)
pol II transcription complex containing 3 Nucleotide long transcript [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA Polymerase II Promoter Opening: First Transition (Canis familiaris)
pol II closed pre-initiation complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II open pre-initiation complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA Polymerase II Transcription Initiation (Canis familiaris)
NTP Binds Active Site of RNA Polymerase II (Canis familiaris)
Pol II initiation complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II open pre-initiation complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Newly Formed Phosphodiester Bond Stabilized and PPi Released (Canis familiaris)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II transcription complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP (Canis familiaris)
Pol II Initiation complex with phosphodiester-PPi intermediate [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Pol II initiation complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening (Canis familiaris)
Binding of TFIIA and TFIIB to the pol II promoter:TFIID complex (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Binding of TFIIE to the growing preinitiation complex (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Formation of the closed pre-initiation complex (Canis familiaris)
pol II closed pre-initiation complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF:TFIIE complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Recruitment of RNA Polymerase II Holoenzyme by TFIIF to the pol II promoter:TFIID:TFIIA:TFIIB complex (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB:Pol II:TFIIF complex [nucleoplasm] (Canis familiaris)
pol II promoter:TFIID:TFIIA:TFIIB complex [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA polymerase II transcribes snRNA genes (Canis familiaris)
CBCAP complex binds 7-methylguanosine cap of snRNA (Canis familiaris)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Canis familiaris)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Canis familiaris)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Integrator complex processes the 3' end of snRNA (Canis familiaris)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Pre-snRNA is elongated and capped with 7-methylguanosine (Canis familiaris)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Canis familiaris)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Canis familiaris)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Canis familiaris)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Canis familiaris)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Estrogen-dependent gene expression (Canis familiaris)
CARM1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Canis familiaris)
CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
Histone acetyltransferases are recruited to the TFF1 gene (Canis familiaris)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1 [nucleoplasm] (Canis familiaris)
CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
ESR1:estrogen:TFF1gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1:HATs [nucleoplasm] (Canis familiaris)
ESR1:estrogen:TFF1 gene:FOXA1:GATA3:DDX5:TBP:TFIIA:CARM1,PRMT1 [nucleoplasm] (Canis familiaris)
CARM1:TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
PRMT1 binds TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene (Canis familiaris)
ESR1:estrogen:TFF1 gene:DDX5:TBP:TFIIA:PRMT1:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter (Canis familiaris)
TBP:TFIIA:DDX5:ESR1:estrogen:TFF1 gene:FOXA1:GATA3 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
TFIIA [nucleoplasm] (Canis familiaris)
GTF2A2 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3P2N9
Gene Names
GTF2A2
Reference Genes
ENSEMBL:ENSCAFG00845016636.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845016636.1 GTF2A2
Other Identifiers
478327
Cfa.9946.1.S1_at
Cfa.9946.2.S1_s_at
GO:0005634
GO:0005654
GO:0005672
GO:0006351
GO:0006367
GO:0043226
GO:0061629
Participates
as a component of
TFIIA [nucleoplasm] (Canis familiaris)
Inferred From
GTF2A2 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000140307
Ensembl
ENSCAFT00845029529
,
ENSCAFG00845016636
,
ENSCAFP00845023196
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