Reactome | RAC1 [ficolin-1-rich granule membrane]

RAC1 [ficolin-1-rich granule membrane]

Stable Identifier

R-CFA-6804802

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

ficolin-1-rich granule membrane

Synonyms

RAC1, P62999

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P62999

Gene Names

RAC1

Reference Genes

BioGPS Gene:403955 RAC1

ENSEMBL:ENSCAFG00030017683

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00030017683 RAC1

ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00040013856 RAC1

KEGG Gene (Canis lupus familiaris):403955 RAC1

Monarch:403955 RAC1

NCBI Gene:403955 RAC1

Reference Transcript

RefSeq:NM_001003274.2 RAC1

Participates

as a member of

Ficolin-rich granule membrane proteins [ficolin-1-rich granule membrane] (Canis familiaris)

Other forms of this molecule

RAC1 [secretory granule membrane]

RAC1 [plasma membrane]

RAC1 [endoplasmic reticulum membrane]

RAC1 [cytosol]

RAC1 [plasma membrane]

Inferred From

RAC1 [ficolin-1-rich granule membrane] (Homo sapiens)

Cross References

RefSeq

NP_001003274.1

OpenTargets

ENSG00000136238

IntEnz

3.6.5.2

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P46940 IQGAP1	3	IQGAP1 [secretory granule membrane] (R-HSA-6804803) IQGAP1 [cytosol] (R-HSA-5626371) IQGAP1 [plasma membrane] (R-HSA-381681)	0.774	5
UniProt:P27986 PIK3R1	15	PIK3R1 K379E [plasma membrane] (R-HSA-8944148) PIK3R1 G376R [plasma membrane] (R-HSA-2399717) PIK3R1 Y463_L466del [plasma membrane] (R-HSA-2399546) PIK3R1 H450_E451del [plasma membrane] (R-HSA-2399545) PIK3R1 R574_T576del [plasma membrane] (R-HSA-2399544) PIK3R1 D560Y [plasma membrane] (R-HSA-2399421) PIK3R1 N564D [plasma membrane] (R-HSA-2399427) PIK3R1 K459del [plasma membrane] (R-HSA-2399554) PIK3R1 N564K [plasma membrane] (R-HSA-2399431) PIK3R1 D560H [plasma membrane] (R-HSA-2399432) PIK3R1 R574I [plasma membrane] (R-HSA-2399536) PIK3R1 R574T [plasma membrane] (R-HSA-2399540) K63polyUb-PIK3R1 [cytosol] (R-HSA-3080572) PIK3R1 [plasma membrane] (R-HSA-198365) PIK3R1 [cytosol] (R-HSA-74789)	0.717	5
UniProt:Q13153 PAK1	6	p-S144-PAK1 [cytosol] (R-HSA-451339) Active PAK1 [cytosol] (R-HSA-8964622) PAK1 [plasma membrane] (R-HSA-3928409) p-S144,T423-PAK1 [plasma membrane] (R-HSA-3928472) PAK1 [cytosol] (R-HSA-162629) p-S144,T423-PAK1 [cytosol] (R-HSA-399819)	0.617	3
UniProt:P42768 WAS	2	p-Y291-WAS [cytosol] (R-HSA-2197668) WAS [cytosol] (R-HSA-201879)	0.469	2

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