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CDC6:ORC:origin complex [nucleoplasm]
Stable Identifier
R-CFA-68543
Type
Complex
Species
Canis familiaris
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
G2/M Checkpoints (Canis familiaris)
Activation of ATR in response to replication stress (Canis familiaris)
Activation of claspin (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
Loading of claspin onto DNA during replication origin firing (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Mitotic G1 phase and G1/S transition (Canis familiaris)
G1/S Transition (Canis familiaris)
Activation of the pre-replicative complex (Canis familiaris)
Cdc45 associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
Cdt1 is displaced from the pre-replicative complex (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
MCM10:pre-replicative complex [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
DNA polymerase alpha:primase binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
DNA polymerase epsilon binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
S Phase (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
Orc1 removal from chromatin (Canis familiaris)
Orc1 is phosphorylated by cyclin A/CDK2 (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
DNA Replication (Canis familiaris)
DNA Replication Pre-Initiation (Canis familiaris)
Activation of the pre-replicative complex (Canis familiaris)
Cdc45 associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
Cdt1 is displaced from the pre-replicative complex (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
MCM10:pre-replicative complex [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
DNA polymerase alpha:primase binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
DNA polymerase epsilon binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
Orc1 removal from chromatin (Canis familiaris)
Orc1 is phosphorylated by cyclin A/CDK2 (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CDC6 [nucleoplasm]
(Canis familiaris)
ORC:origin of replication [nucleoplasm]
(Canis familiaris)
Participates
as a component of
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
Inferred From
CDC6:ORC:origin complex [nucleoplasm]
(Homo sapiens)
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