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MCM3 [nucleoplasm]
Stable Identifier
R-CFA-68546
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
MCM3, A0A8I3N9W3
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
G2/M Checkpoints (Canis familiaris)
Activation of ATR in response to replication stress (Canis familiaris)
Activation of claspin (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:Activated claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Loading of claspin onto DNA during replication origin firing (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Mitotic G1 phase and G1/S transition (Canis familiaris)
G1/S Transition (Canis familiaris)
Activation of the pre-replicative complex (Canis familiaris)
Cdc45 associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Cdt1 is displaced from the pre-replicative complex. (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
MCM10:pre-replicative complex [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
DNA polymerase alpha:primase binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
DNA polymerase epsilon binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
S Phase (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
Mcm4,6,7 trimer forms and associates with the replication fork (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Orc1 removal from chromatin (Canis familiaris)
Orc1 is phosphorylated by cyclin A/CDK2 (Canis familiaris)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
DNA Replication (Canis familiaris)
DNA Replication Pre-Initiation (Canis familiaris)
Activation of the pre-replicative complex (Canis familiaris)
Cdc45 associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Cdt1 is displaced from the pre-replicative complex. (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
MCM10:pre-replicative complex [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
DNA polymerase alpha:primase binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
DNA polymerase epsilon binds at the origin (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Canis familiaris)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM10:active pre-replicative complex [nucleoplasm] (Canis familiaris)
active pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Assembly of the pre-replicative complex (Canis familiaris)
Formation of MCM2-7 complex (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
MCM3 binds MCM5 (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Synthesis of DNA (Canis familiaris)
Switching of origins to a post-replicative state (Canis familiaris)
Mcm4,6,7 trimer forms and associates with the replication fork (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
Orc1 removal from chromatin (Canis familiaris)
Orc1 is phosphorylated by cyclin A/CDK2 (Canis familiaris)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
pre-replicative complex [nucleoplasm] (Canis familiaris)
MCM2-7 [nucleoplasm] (Canis familiaris)
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
MCM3 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3N9W3
Gene Names
MCM3
Reference Genes
ENSEMBL:ENSCAFG00845008858.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845008858.1 MCM3
Other Identifiers
481839
CfaAffx.4185.1.S1_at
CfaAffx.4188.1.S1_s_at
GO:0000166
GO:0000228
GO:0003677
GO:0003824
GO:0004386
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0006260
GO:0006268
GO:0006270
GO:0007049
GO:0016787
GO:0016887
GO:0032508
GO:0042555
GO:0043226
GO:0048471
GO:0071162
GO:0140657
Participates
as an output of
Mcm4,6,7 trimer forms and associates with the replication fork (Canis familiaris)
as an input of
MCM3 binds MCM5 (Canis familiaris)
as a component of
MCM3:MCM5 [nucleoplasm] (Canis familiaris)
Inferred From
MCM3 [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000112118
Ensembl
ENSCAFG00845008858
,
ENSCAFT00845015709
,
ENSCAFP00845012219
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