Reactome | RB1 [nucleoplasm]

RB1 [nucleoplasm]

Stable Identifier

R-CFA-68642

Type

Protein [EntityWithAccessionedSequence]

Species

Canis familiaris

Compartment

nucleoplasm

Synonyms

RB1, A0A8I3PSW0

Locations in the PathwayBrowser

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Cellular responses to stimuli (Canis familiaris)

- Cellular responses to stress (Canis familiaris)
  - Cellular Senescence (Canis familiaris)
    - DNA Damage/Telomere Stress Induced Senescence (Canis familiaris)
      - Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Canis familiaris)
        
        SAHF formation (Canis familiaris)
        
        RB1 [nucleoplasm] (Canis familiaris)

Gene expression (Transcription) (Canis familiaris)

- Epigenetic regulation of gene expression (Canis familiaris)
  - Epigenetic regulation by WDR5-containing histone modifying complexes (Canis familiaris)
    - Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Canis familiaris)
      - Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Canis familiaris)
        
        MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Canis familiaris)
        
        Unliganded PPARG:RXRA heterodimer recruits corepressors to target gene loci (Canis familiaris)
        
        RB1 [nucleoplasm] (Canis familiaris)

External Reference Information

External Reference

UniProt:A0A8I3PSW0

Gene Names

RB1

Reference Genes

ENSEMBL:ENSCAFG00845025645.1

UCSC:A0A8I3PSW0 RB1

Other Identifiers

Cfa.3598.1.S1_at

CfaAffx.7597.1.S1_at

GO:0000082

GO:0000122

GO:0001558

GO:0001894

GO:0002062

GO:0003180

GO:0005634

GO:0005654

GO:0005667

GO:0005737

GO:0005819

GO:0006325

GO:0006351

GO:0006355

GO:0006357

GO:0006366

GO:0006915

GO:0007224

GO:0007265

GO:0007346

GO:0008024

GO:0008283

GO:0008285

GO:0010629

GO:0012501

GO:0014009

GO:0016605

GO:0019899

GO:0019900

GO:0030154

GO:0030182

GO:0030308

GO:0031134

GO:0031175

GO:0031507

GO:0031625

GO:0032869

GO:0034088

GO:0034349

GO:0035189

GO:0035914

GO:0042551

GO:0042802

GO:0043226

GO:0043353

GO:0045445

GO:0045651

GO:0045786

GO:0045842

GO:0045879

GO:0045892

GO:0045930

GO:0045944

GO:0048565

GO:0048667

GO:0048856

GO:0050673

GO:0050680

GO:0050728

GO:0051146

GO:0051219

GO:0051276

GO:0051301

GO:0051402

GO:0051726

GO:0060253

GO:0060255

GO:0061629

GO:0061676

GO:0061793

GO:0071459

GO:0071466

GO:0080090

GO:0097284

GO:0097718

GO:0120163

GO:0140297

GO:1903055

GO:1904028

GO:1904761

GO:2000045

GO:2000134

Participates

as an input of

as a component of

as an output of

This entity regulates

Positively

Other forms of this molecule

phospho-RB1 [nucleoplasm]

RB1 [cytosol]

phospho-RB1 [nucleoplasm]

Inferred From

RB1 [nucleoplasm] (Homo sapiens)

Cross References

ENSEMBL

ENSCAFT00845046821, ENSCAFP00845036721