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About
What is Reactome ?
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Team
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Release Calendar
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Our Logo
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Privacy Notice
Disclaimer
Digital Preservation
Contact us
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Table of Contents
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Docs
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How do I search ?
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PAMP:NOD oligomer [cytosol]
Stable Identifier
R-CFA-708346
Type
Set [DefinedSet]
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-17 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Canis familiaris)
NOD1/2 Signaling Pathway (Canis familiaris)
Activated NOD oligomer recruites RIP2 (RICK) (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
CYLD deubiquitinates NEMO (Canis familiaris)
PAMP:NOD oligomer:RIP2:K63-Ub-K285-NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
K63 polyubiquitinated RIP2 associates with the TAK1 complex (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
RIP2 binds NEMO (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
RIP2 induces K63-linked ubiquitination of NEMO (Canis familiaris)
PAMP:NOD oligomer:RIP2:K63-Ub-K285-NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
RIP2 is K63 polyubiquitinated (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
TAK1 is activated (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
TNFAIP3 (A20) deubiquitinates RIP2 (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88-independent TLR4 cascade (Canis familiaris)
TRIF (TICAM1)-mediated TLR4 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Deubiquitination (Canis familiaris)
Ovarian tumor domain proteases (Canis familiaris)
TNFAIP3 (A20) deubiquitinates RIP2 (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Participants
members
NOD1:iE-DAP oligomer [cytosol]
(Canis familiaris)
MDP:NOD2 oligomer [cytosol]
(Canis familiaris)
Participates
as an input of
Activated NOD oligomer recruites RIP2 (RICK) (Canis familiaris)
as a component of
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
Inferred From
PAMP:NOD oligomer [cytosol]
(Homo sapiens)
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