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About
What is Reactome ?
News
Team
Scientific Advisory Board
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Release Calendar
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Our Logo
License Agreement
Privacy Notice
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Digital Preservation
Contact us
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Table of Contents
DOIs
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Docs
Userguide
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How do I search ?
Details Panel
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Cytomics
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Go!
MDP:NOD2 oligomer [cytosol]
Stable Identifier
R-CFA-708350
Type
Complex
Species
Canis familiaris
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Signaling by Interleukins (Canis familiaris)
Interleukin-17 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Innate Immune System (Canis familiaris)
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Canis familiaris)
NOD1/2 Signaling Pathway (Canis familiaris)
Activated NOD oligomer recruites RIP2 (RICK) (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Activated NOD2 oligomerizes (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
CYLD deubiquitinates NEMO (Canis familiaris)
PAMP:NOD oligomer:RIP2:K63-Ub-K285-NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
K63 polyubiquitinated RIP2 associates with the TAK1 complex (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
RIP2 binds NEMO (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
RIP2 induces K63-linked ubiquitination of NEMO (Canis familiaris)
PAMP:NOD oligomer:RIP2:K63-Ub-K285-NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
RIP2 is K63 polyubiquitinated (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
TAK1 is activated (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:TAK1 complex [plasma membrane] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
TNFAIP3 (A20) deubiquitinates RIP2 (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88-independent TLR4 cascade (Canis familiaris)
TRIF (TICAM1)-mediated TLR4 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
Activated TAK complexes [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO:activated TAK1 complex [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Deubiquitination (Canis familiaris)
Ovarian tumor domain proteases (Canis familiaris)
TNFAIP3 (A20) deubiquitinates RIP2 (Canis familiaris)
PAMP:NOD oligomer:K63-polyUb-RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:K63-Ub-RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2:NEMO [cytosol] (Canis familiaris)
PAMP:NOD oligomer:RIP2 [cytosol] (Canis familiaris)
PAMP:NOD oligomer [cytosol] (Canis familiaris)
MDP:NOD2 oligomer [cytosol] (Canis familiaris)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 6
MDP:NOD2 [cytosol]
(Canis familiaris)
Participates
as an output of
Activated NOD2 oligomerizes (Canis familiaris)
as a member of
PAMP:NOD oligomer [cytosol] (Canis familiaris)
Inferred From
MDP:NOD2 oligomer [cytosol]
(Homo sapiens)
© 2024
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