Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
LOC608162 [cytosol]
Stable Identifier
R-CFA-72347
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
RPS2, A0A8I3N9X5
Locations in the PathwayBrowser
Expand all
Chromatin organization (Canis familiaris)
Chromatin modifying enzymes (Canis familiaris)
RMTs methylate histone arginines (Canis familiaris)
PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Metabolism of RNA (Canis familiaris)
Nonsense-Mediated Decay (NMD) (Canis familiaris)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Canis familiaris)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Canis familiaris)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
SMG6 hydrolyzes mRNA with premature termination codon (Canis familiaris)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Canis familiaris)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Canis familiaris)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Canis familiaris)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Canis familiaris)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
rRNA processing (Canis familiaris)
rRNA processing in the nucleus and cytosol (Canis familiaris)
Major pathway of rRNA processing in the nucleolus and cytosol (Canis familiaris)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Protein methylation (Canis familiaris)
PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Translation (Canis familiaris)
Eukaryotic Translation Initiation (Canis familiaris)
Cap-dependent Translation Initiation (Canis familiaris)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Canis familiaris)
Translation initiation complex formation (Canis familiaris)
Formation of translation initiation complexes containing mRNA that does not circularize (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
48S complex [cytosol] (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Formation of a pool of free 40S subunits (Canis familiaris)
Release of 40S and 60S subunits from the 80S ribosome (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
eIF3 and eIF1A bind to the 40S subunit (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
40S:eIF3:eIF1A [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Formation of the ternary complex, and subsequently, the 43S complex (Canis familiaris)
Formation of the 43S pre-initiation complex (Canis familiaris)
40S:eIF3:eIF1A [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
GTP hydrolysis and joining of the 60S ribosomal subunit (Canis familiaris)
The 60S subunit joins the translation initiation complex (Canis familiaris)
40S:Met-tRNAi:mRNA [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
eIF2:GTP is hydrolyzed, eIFs are released (Canis familiaris)
40S:Met-tRNAi:mRNA [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
48S complex [cytosol] (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
eIF5B:GTP is hydrolyzed and released (Canis familiaris)
80S:Met-tRNAi:mRNA [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Ribosomal scanning and start codon recognition (Canis familiaris)
Ribosomal scanning (Canis familiaris)
48S complex [cytosol] (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
Start codon recognition (Canis familiaris)
48S complex [cytosol] (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
L13a-mediated translational silencing of Ceruloplasmin expression (Canis familiaris)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Canis familiaris)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Canis familiaris)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Canis familiaris)
43S complex [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
SRP-dependent cotranslational protein targeting to membrane (Canis familiaris)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Canis familiaris)
SRP:polypeptide+signal:ribosome [cytosol] (Canis familiaris)
ribosome:mRNA:polypeptide+signal [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
ribosome:mRNA:polypeptide+signal [cytosol] (Canis familiaris)
80S ribosome [cytosol] (Canis familiaris)
40S ribosomal complex [cytosol] (Canis familiaris)
LOC608162 [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3N9X5
Gene Names
LOC608162
Reference Genes
ENSEMBL:ENSCAFG00845008913.1
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00845008913.1 LOC608162
Other Identifiers
608162
Cfa.12418.1.S1_s_at
CfaAffx.374.1.S1_s_at
GO:0003723
GO:0003735
GO:0005198
GO:0005840
GO:0006412
GO:0015935
GO:0043226
Participates
as an input of
PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Canis familiaris)
as a component of
40S ribosomal complex [cytosol] (Canis familiaris)
This entity regulates
Positively
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA
(Canis familiaris)
Other forms of this molecule
LOC608162 [nucleoplasm]
LOC608162 [cytosol]
Inferred From
RPS2 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSCAFP00845012178
,
ENSCAFT00845015660
,
ENSCAFG00845008913
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text