Reactome | Insulin:p-6Y-Insulin receptor [plasma membrane]

Insulin:p-6Y-Insulin receptor [plasma membrane]

Stable Identifier

R-CFA-74678

Type

Complex

Species

Canis familiaris

Compartment

plasma membrane

Locations in the PathwayBrowser

Expand all

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Insulin [extracellular region] (Canis familiaris)
p-6Y-insulin receptor [plasma membrane] (Canis familiaris)

Participates

as an input of

Binding of Grb10 to the insulin receptor (Canis familiaris)
Binding of IRS to insulin receptor (Canis familiaris)
Binding of SHC1 to insulin receptor (Canis familiaris)
Internalisation of the insulin receptor (Canis familiaris)

as a candidate of

Activated SRC,LCK,EGFR,INSR [plasma membrane] (Canis familiaris)

as an output of

Dissociation of IRS-P from insulin receptor (Canis familiaris)
Dissociation of p-Y427-SHC1 from insulin receptor (Canis familiaris)
Autophosphorylation of insulin receptor (Canis familiaris)

as a component of

Insulin:p-6Y-Insulin receptor:SHC1 [plasma membrane] (Canis familiaris)
Insulin:p-6Y-Insulin receptor:p-Y427-SHC1 [plasma membrane] (Canis familiaris)
GRB10:INSR [plasma membrane] (Canis familiaris)
IRS:Insulin:p-6Y-Insulin receptor [plasma membrane] (Canis familiaris)
p-Y-IRS:Insulin:p-6Y-Insulin receptor [plasma membrane] (Canis familiaris)

Inferred From

Insulin:p-6Y-Insulin receptor [plasma membrane] (Homo sapiens)

Cite Us!