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LOC487737 [plasma membrane]
Stable Identifier
R-CFA-877333
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
plasma membrane
Synonyms
IFNAR2-2, A0A5F4C8N5
Locations in the PathwayBrowser
Expand all
Immune System (Canis familiaris)
Cytokine Signaling in Immune system (Canis familiaris)
Interferon Signaling (Canis familiaris)
Interferon alpha/beta signaling (Canis familiaris)
Activation of JAK kinases (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
p-TYK2:p-IFNAR1:SOCS-1/SOCS-3:IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
Formation of p-STAT1 homodimer (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFN alpha/beta binds to IFNAR2 (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2:type 1 interferon analogs [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 binds JAK1,2 inhibitors (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2:JAK1,2 inhibitors [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 binds type 1 interferon analogs (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2:type 1 interferon analogs [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
Phosphorylation of INFAR1 by TYK2 (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
Phosphorylation of STAT2 (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
Recruitment of IFNAR1 (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
Recruitment of STAT2 to p-IFNAR1 (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
Regulation of IFNA/IFNB signaling (Canis familiaris)
Dephosphorylation of JAK1 by SHP1 (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
Dephosphorylation of STAT1 by SHP2 (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:STAT1 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
Dephosphorylation of TYK2 by PTP1B (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
UBP43 binds IFNAR2 and prevents JAK1 interaction (Canis familiaris)
IFNAR2c:UBP43 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
Release of p-STAT2:p-STAT1 dimer (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
LOC487737 [plasma membrane] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A5F4C8N5
Gene Names
LOC487737
Reference Genes
ENSEMBL:ENSCAFG00000009065
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000009065 LOC487737
Participates
as an input of
UBP43 binds IFNAR2 and prevents JAK1 interaction (Canis familiaris)
as a component of
IFNAR2c:UBP43 [plasma membrane] (Canis familiaris)
IFNAR2:JAK1:STAT2 [plasma membrane] (Canis familiaris)
IFNAR2:p-JAK1:STAT2 [plasma membrane] (Canis familiaris)
Inferred From
IFNAR2-2 [plasma membrane]
(Homo sapiens)
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