Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SKIC8 [nucleoplasm]
Stable Identifier
R-CFA-8866696
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
nucleoplasm
Synonyms
WDR61, A0A8I3MWR4
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
RNA Polymerase II Pre-transcription Events (Canis familiaris)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Canis familiaris)
Paused processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Canis familiaris)
Processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Abortive termination of elongation after arrest (Canis familiaris)
Aborted elongation complex after arrest [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Elongating transcript encounters a lesion in the template (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Resumption of elongation after recovery from pausing (Canis familiaris)
Paused processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
TFIIS-mediated recovery of elongation from arrest (Canis familiaris)
Processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
RNA Polymerase II Transcription Elongation (Canis familiaris)
Addition of nucleotides leads to transcript elongation (Canis familiaris)
Elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Formation of RNA Pol II elongation complex (Canis familiaris)
Recruitment of elongation factors to form elongation complex (Canis familiaris)
Elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Pol II elongation complex moves on the template as transcript elongates (Canis familiaris)
Elongation complex prior to separation [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Processive elongation complex [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Separation of elongating transcript from template (Canis familiaris)
Elongation complex prior to separation [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Protein ubiquitination (Canis familiaris)
E3 ubiquitin ligases ubiquitinate target proteins (Canis familiaris)
RNF20:RNF40 binds PAF complex, Ubiquitin:UBE2A,B (Ubiquitin:RAD6), WAC and Histone H2B (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
RNF20:RNF40 monoubiquitinates Histone H2B (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
PAF1c:WAC:RNF20:RNF40:Ub:UBE2A,B:HIST1H2B [nucleoplasm] (Canis familiaris)
PAF1C [nucleoplasm] (Canis familiaris)
SKIC8 [nucleoplasm] (Canis familiaris)
External Reference Information
External Reference
UniProt:A0A8I3MWR4
Gene Names
SKIC8
Reference Genes
ENSEMBL:ENSCAFG00845007438.1
UCSC:A0A8I3MWR4 SKIC8
Reference Transcript
RefSeq:XM_536215.5 SKIC8
Other Identifiers
479068
Cfa.1052.1.A1_at
CfaAffx.21953.1.S1_at
CfaAffx.21953.1.S1_s_at
GO:0016593
Participates
as a component of
PAF1C [nucleoplasm] (Canis familiaris)
Other forms of this molecule
SKIC8 [cytosol]
Inferred From
WDR61 [nucleoplasm]
(Homo sapiens)
Cross References
ENSEMBL
ENSCAFG00845007438
,
ENSCAFP00845010216
,
ENSCAFT00845013134
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
